Atmospheric deposition is an important pathway for air pollutants entering the environment. In order to better understand both dry and wet deposition of PCDD/Fs in ambient air, two cities - Guangzhou and Nanjing in Southern China, were investigated. The monthly dry deposition fluxes of total-PCDD/Fs-WHO_(2005)-TEQ were in the range of 60.6- 560 and 104-1160 pg WHO_(2005)-TEQ m^(-2) month^(-1) during 2014 in Guangzhou and Nanjing, respectively. In addition, it was found that the monthly dry deposition velocities of particle phase PCDD/Fs-TEQ ranged between 0.49 and 0.98 cm s^(-1) (averaged 0.69 cm s^(-1)) and between 0.44 and 0.8 cm s^(-1) (averaged 0.52 cm s^(-1)) in Guangzhou and Nanjing, respectively. The average scavenging ratios of total-PCDD/Fs-WHO_(2005)-TEQ were 20480 and 30947 in Guangzhou and Nanjing, respectively. The total (dry + wet) deposition fluxes in Nanjing ranged between 135 and 1250, and averaged 643 pg WHO_(2005)-TEQ m^(-2) month^(-1), approximatedly1.38-2.23 times of magnitude higher than those in Guangzhou, which ranged between 97.7 to 559 pg WHO_(2005)-TEQ m^(-2) month^(-1) and averaged 254 pg WHO_(2005)-TEQ m^(-2) month^(-1). The results of this study provide useful information for both further studies and environmental control strategies aimed at persistent organic compounds (POPs).