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- OpenAccess
Thermal-Desorption Proton-Transfer-Reaction Quadruple-Interface Time-of-Flight Mass Spectrometry: Online Analysis of Organic Aerosol Using Single-Component Particles
摘要
A proton transfer reaction-quadrupole interface time-of-flight mass spectrometer was combined with a hand-made thermal desorption (TD) instrument for real-time analysis of organic aerosol particles. Size-selected single-component organic particles were generated using a nebulizer combined with a differential mobility analyzer. We tested perfluoroalkoxy alkene (PFA) and copper tubing for the TD instrument. Higher signal intensities were observed when using PFA tubing, suggesting that wall deposition loss of vaporized semi-volatile organic compounds was suppressed when PFA tubing was used. Protonated molecules, [M + H]^+, had the highest intensity in the mass spectrum of dialdehyde particles (i.e., terephthaldialdehyde), whereas ions formed by dehydration from protonated molecules, [M + H - H_2O]^+, had the highest intensities in the mass spectra of carboxylic acid particles (i.e., adipic, phthalic, and cis-pinonic acids) and alcohol particles (i.e., meso-erythritol). The mass spectra obtained for organic aerosol markers will be useful to interpret mass spectra measured for organic aerosol particles by TD-proton transfer reaction-mass spectrometry.
延伸閱讀
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- Kaul, D. S., Ning, Z., Westerdahl, D., Yin, X., & Cary, R. A. (2016). A Novel Tandem of Thermal Desorption Carbon Analyzer and Off-Axis Integrated Cavity Output Spectroscopy for Aerosol Stable Carbon Isotope Ratio Measurement. Aerosol and Air Quality Research, 16(6), 1345-1355. https://doi.org/10.4209/aaqr.2015.05.0288
- Porta T、Varesio E、Hopfgartner G、莊諭霖、姜謙達（2014）。Gas-Phase Separation of Drugs and Metabolites Using Modifier-Assisted Differential Ion Mobility Spectrometry Hyphenated to Liquid Extraction Surface Analysis and Mass Spectrometry。台灣法醫學誌，6(1)，88-88。https://doi.org/10.6134/tjfm.2014.0601.15
- Avino, P., Lopez, F., & Manigrasso, M. (2013). Regional Deposition of Submicrometer Aerosol in the Human Respiratory System Determined at 1-s Time Resolution of Particle Size Distribution Measurements. Aerosol and Air Quality Research, 13(6), 1702-1711. https://doi.org/10.4209/aaqr.2013.06.0189
- 陳云萱、歐宇祥、蔡岳廷、蔡文城（2016）。Performance of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry in the Identification of Aerobic Non-fastidious Gram-Negative Bacilli Commonly Encountered in a Clinical Laboratory。檢驗及品保雜誌，5(4)，123-131。https://doi.org/10.6573/JTQA.201612_5(4).01