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Establishment of a Predictive Model of Serum Glucose Changes under Different Exercise Intensities and Durations among Patients with Type 2 Diabetes Mellitus

第二型糖尿病患者不同運動強度、時間下血糖變異量預測模式之建立

摘要


規律運動一直被視為治療糖尿病的要素之一,因此本研究目的在探討不同運動強度和時間,對運動後血糖變異量之影響,並建立不同運動強度和時間,對血糖變異量之預測模式。本研究收集第2 型糖尿病患者共37 位,在經由運動測試後,根據其運動測試結果,設計12 次不同運動強度 (40%、60%和80% 最大工作負荷量) 和運動時間 (10、20、30 和40 分) 之運動計劃,並與運動前、後測量其血糖值,研究結果顯示,運動強度和運動時間會影響血糖的變化量,但運動強度和時間的交互作用,對血糖的變化量並無影響。運動強度、時間、運動前血糖值和性別四項,共可解釋運動後血糖值變異量達37%。本研究結果支持運動量與血糖變異量的預測關係,將有助於醫護人員教導第2 型糖尿病患者,在不同運動情境下預期血糖的變化。

並列摘要


Regular exercise is regarded as one of necessary elements in treating diabetes mellitus (DM). The purpose of this study was to investigate the influence of different exercise intensities and durations on serum glucose changes after exercise in type 2 DM patients and to establish a predictive model of changes in serum glucose under different exercise intensities and durations. Thirty-seven type 2 DM patients were recruited from four teaching hospitals. A total of 12 exercise sessions were scheduled according to the results of a graded treadmill exercise test. The 12 exercise sessions were designed on the basis of different exercise intensities (40%, 60%, and 80% maximal workload) and exercise durations (10, 20, 30, and 40 min). Serum glucose level was measured before and after exercise. The findings indicate that the main effect of exercise intensity and duration was significant, but there was no interaction effect. All four variables, including exercise intensity, exercise duration, pre-exercise serum glucose levels, and gender, explained 37% of the variance in serum glucose changes after exercise. In conclusion, a dose-response relationship between exercise amount and serum glucose changes was demonstrated. This is helpful for health professionals to teach type 2 DM patients how to predict serum glucose response in different exercise situations.

參考文獻


Albright, A., Franz, M., Hornsby, G., Kriska, A., Marrero, D., Ullrich, I., Verity, L. S.(2000).American College of Sports Medicine Position Stand. Exercise and Type 2 Diabetes.Medicine & Science in Sports & Exercise.32(7)
American College of Sports Medicine(2001).ACSM'S Resource Manual for Guidelines for Exercise Testing and Prescription.Baltimore, MD:Williams & Wilkins.
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Boule, N. G., Haddad, E., Kenny, G. P., Wells, G. A., Sigal, R. J.(2001).Effects of Exercise on Glycemic Control and Body Mass in Type 2 Diabetes Mellitus: A Meta-Analysis of Controlled Clinical Trials.The Journal of the American Medical Association.286(10)
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