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Effectiveness of Propolis on Oral Health: A Meta-Analysis

蜂膠對口腔健康的成效:統合分析

摘要


背景 過去十年,以蜂膠漱口液或凝膠做為輔助療法,在台灣已日漸增多。然而,蜂膠對口腔健康的成效,人們尚未熟知。目的 本統合分析旨在蒐集最佳實證,以呈現蜂膠對人口腔健康的成效,包括口腔感染、牙菌斑、與口內炎。方法 搜尋七個電子資料庫,於1969-2012年出版之研究論文,依納入及排除條件篩選後,繼而以Joanna Briggs Institute的量性文章評讀工具做文獻品質評值。結果 八篇在1997-2011年出版,共194位受試者有數值可供分析。統合分析顯示,蜂膠對減少牙菌斑量有成效,但未達統計學上的顯著差異;口腔感染或口內炎也未見統計學上的差異。結論/實務應用 雖然略見蜂膠成效,但限於研究數量與品質之不足,研究間的變異性大。本統合分析建議需有更佳設計的試驗,以取得較周全的結論。

關鍵字

蜂膠 口腔感染 牙斑 口內炎

並列摘要


Background: The use of propolis mouth rinse or gel as a supplementary intervention has increased during the last decade in Taiwan.However, the effect of propolis on oral health is notwell understood. Purpose: The purpose of thismeta-analysis was to present the best available evidence regarding the effects of propolis use on oral health, including oral infection, dental plaque, and stomatitis. Methods: Researchers searched seven electronic databases for relevant articles published between 1969 and 2012. Data were collected using inclusion and exclusion criteria. The Joanna Briggs Institute Meta Analysis of Statistics Assessment and Review Instrumentwas used to evaluate the quality of the identified articles. Results: Eight trials published from 1997 to 2011 with 194 participants had extractable data. The result of the meta-analysis indicated that, although propolis had an effect on reducing dental plaque, this effect was not statistically significant. The resultswere not statistically significant for oral infection or stomatitis. Conclusions/Implications for Practice: Although there are a number of promising indications, in view of the limited number and quality of studies and the variation in results among studies, this review highlights the need for additional well-designed trials to draw conclusions that are more robust.

並列關鍵字

propolis oral infection dental plaque stomatitis

參考文獻


Bankova, V.(2005).Recent trends and important developments in propolis research.Evidence-based Complementary and Alternative Medicine.2(1),29-32.
Blonska, M.,Bronikowska, J.,Pietsz, G.,Czuba, Z. P.,Scheller, S.,Krol, W.(2004).Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages.Journal of Ethnopharmacolgy.91(1),25-30.
Borrelli, F.,Maffia, P.,Pinto, L.,Ianaro, A.,Russo, A.,Capasso, F.,Ialenti, A.(2002).Phytochemical compounds involved in the anti-inflammatory effect of propolis extract.Fitoterapia.73(1, Suppl.),S53-S63.
Casaroto, A. R.,Lara, V. S.(2010).Phytomedicines for Candida-associated denture stomatitis.Fitoterapia.81(5),323-328.
Castaldo, S.,Capasso, F.(2002).Propolis, an old remedy used in modern medicine.Fitoterapia.73(1, Suppl.),S1-S6.

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