台灣成年人腸激躁症與精神症狀的相關性研究

The Relationship between Irritable Bowel Syndrome and Psychiatric Symptoms in a Taiwanese Adult Population

侯宜彣(Yi-Wen Hou) ； 吳晉祥(Jin-Shang Wu) ； 楊宜青(Yi-Ching Yang) ； 黃雅靖(Ya-Chin Huang) ； 葉宗烈(Tzung-Lieh Yeh) ； 盧豐華(Feng-Hwa Lu) ； 張智仁(Chih-Jen Chang)

《台灣家庭醫學雜誌》 19卷4期 (2009/12) Pp. 181-191

https://doi.org/10.7023/TJFM.200912.0181

摘要

Purpose: It has been suggested that psychiatric symptoms including anxiety, depression, somatization disorder, panic disorders and phobias are associated with irritable bowel syndrome (IBS). The effect of psychiatric symptoms on IBS has been inconsistent and previous studies had not been adjusted for other confounding factors. The aim of this study was to investigate the relationship between psychiatric symptoms and IBS in a Taiwanese population.
Methods: A total of 2,558 subjects receiving health check-ups in a medical center were recruited. Each subject completed structured questionnaires including the Rome Ⅱ diagnostic questionnaire for IBS and the brief symptom rating scale (BSRS). The BSRS consists of 50 items measuring ten subscales including somatization, obsession, interpersonal sensitivity, depression, anxiety, hostility, phobia, paranoid ideation, psychoticism and addition. The scores for the global severity index (GSI) and ten subscales were assessed to determine the severity of psychiatric symptoms.
Results: Two hundred and seventeen subjects (8.5%) fulfilled the Rome II diagnostic criteria for IBS. Univariate analysis showed that the subjects with IBS were younger, had a higher percentage of habitual drinking, a higher level of triglycerides and higher scores on both the GSI and its ten subscales than did the subjects without IBS. There were significant differences in level of education and marital status between subjects with and without IBS. Subjects with higher GSI scores (odds ratio: 3.340), a high-school education (odds ratio: 1.958), and an elementary-school education or less (odds ratio: 3.978) had a higher risk for IBS after adjusting for age, sex, marital status, obesity, hypertension, diabetes mellitus, alcohol, tea, or coffee consumption, smoking and exercise habits. In other models, individual subscales were substituted for GSI for further multivariate analyses. The risk of IBS increased as each subscale score increased (odds ratio: 1.975-2.917).
Conclusions: A low education level was statistically significantly associated with IBS in a Taiwanese population as were multiple psychiatric symptoms. An integrative evaluation of psychiatric symptoms is recommended in patients with IBS.

並列摘要

Purpose: It has been suggested that psychiatric symptoms including anxiety, depression, somatization disorder, panic disorders and phobias are associated with irritable bowel syndrome (IBS). The effect of psychiatric symptoms on IBS has been inconsistent and previous studies had not been adjusted for other confounding factors. The aim of this study was to investigate the relationship between psychiatric symptoms and IBS in a Taiwanese population.
Methods: A total of 2,558 subjects receiving health check-ups in a medical center were recruited. Each subject completed structured questionnaires including the Rome Ⅱ diagnostic questionnaire for IBS and the brief symptom rating scale (BSRS). The BSRS consists of 50 items measuring ten subscales including somatization, obsession, interpersonal sensitivity, depression, anxiety, hostility, phobia, paranoid ideation, psychoticism and addition. The scores for the global severity index (GSI) and ten subscales were assessed to determine the severity of psychiatric symptoms.
Results: Two hundred and seventeen subjects (8.5%) fulfilled the Rome II diagnostic criteria for IBS. Univariate analysis showed that the subjects with IBS were younger, had a higher percentage of habitual drinking, a higher level of triglycerides and higher scores on both the GSI and its ten subscales than did the subjects without IBS. There were significant differences in level of education and marital status between subjects with and without IBS. Subjects with higher GSI scores (odds ratio: 3.340), a high-school education (odds ratio: 1.958), and an elementary-school education or less (odds ratio: 3.978) had a higher risk for IBS after adjusting for age, sex, marital status, obesity, hypertension, diabetes mellitus, alcohol, tea, or coffee consumption, smoking and exercise habits. In other models, individual subscales were substituted for GSI for further multivariate analyses. The risk of IBS increased as each subscale score increased (odds ratio: 1.975-2.917).
Conclusions: A low education level was statistically significantly associated with IBS in a Taiwanese population as were multiple psychiatric symptoms. An integrative evaluation of psychiatric symptoms is recommended in patients with IBS.

並列關鍵字

irritable bowel syndrome ； psychiatric symptoms ； brief symptom rating scale