Meigs症候群是指良性卵巢腫瘤伴隨腹水和胸腔積液,在腫瘤切除後腹水及胸腔積液將跟著治癒。Meigs症候群的卵巢腫瘤是纖維瘤,腫瘤切除後將不再復發。此疾病沒有特別的臨床症狀,但病人因為會有一些主訴,如疲勞、乾咳、呼吸急促、腹圍增加、腹脹或體重減輕而至家庭醫學科門診就診。經過初步評估,臨床醫師將會注意到一些類似惡性症狀,如骨盆腔腫瘤、腹水、胸水和血清CA-125升高。但這是一個良性疾病,如果處理得當將具有很好的預後。我們報告一位以腹脹及大便習慣改變為初期表徵而後被診斷為Meigs症候群的少數病例。本文的目的是要提醒臨床醫師如果病人主訴疲勞、乾咳、呼吸急促、腹圍增加、腹脹或體重減輕等症狀時務必要將Meigs症候群列入鑑別診斷,並希望藉此病例及文獻回顧,能讓基層醫師對此一少見病症有較深入的了解。(台灣家醫誌2011; 21: 141-148)
Meigs' syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. The ovarian tumor in Meigs' syndrome is a fibroma. No particular clinical symptoms but vague chief complaints such as fatigue, nonproductive cough, shortness of breath, abdominal bloating or weight loss is often encountered in the clinics of Family Medicine Department. After primary survey, mimics a malignant condition such as pelvic tumor, ascites, hydrothorax and elevated serum Carbohydrate Antigen-125 (CA-125) will be noted. But it is a benign disease with very good prognosis if properly managed. We report a case of Meigs' syndrome presented with nonproductive cough, shortness of breath, abdominal fullness and changed of bowel habit with tiny stool passaged as an initial manifestation. The purpose of this paper is to remind clinicans to consider Meigs' syndrome as a differential diagnosis of vague chief complaints of fatigue, nonproductive cough, shortness of breath, abdominal bloating or weight loss. (Taiwan J Fam Med 2011; 21: 141-148)