台灣南部海水魚養殖場正常魚隻分離菌之抗菌劑感受性調查

Antimicrobial Susceptibility in Bacterial Isolated from Normal Seawater Fish Farm in Southern Taiwan

蔡慧玲(Hue-Lin Tsai) ； 馬英萍(Yinq-Pinq Ma) ； 郭鴻志(Honq-Jyh Kuo) ； 林上海(Shang-Hai Lin) ； 涂堅(Chien Tu) ； 張紹光(Shao-Kuang Chang)

《臺灣獸醫學雜誌》 31卷4期 (2005/12) Pp. 274-280

https://doi.org/10.7009/TVJ.200512.0274

摘要

本研究針對南部二十五家海水魚養殖場中正常魚隻鰓部、消化道與池水分離菌進行常用抗菌劑的感受性調查。選定的目標菌包括弧菌（Vibrio spp.）、產氣單胞菌（Aeromonas spp.）、假單胞桿菌（Pseudomonas spp.）、巴斯德桿菌（Pasteurella spp.）、大腸桿菌（Escherichia coli）及沙門氏桿菌（Salmonella spp.）、葡萄球菌（Staphylococcus spp.）、鏈球菌（Streptococcus spp.）及腸球菌（Enterococcus spp.）。三種來源中，主要分離菌的種類並無明顯的差異。另經紙錠擴散法的藥物感受性試驗結果得知胺嘧啶、磺胺二甲基嘧啶、安默西林、羥四環素與氯黴素均已具高度抗藥性，但對富來頓、健牠黴素與奎諾酮類抗菌劑較具有感受性。由於選定分離菌已見對多種抗菌劑產生抗藥性，因此，建議養殖界在臨床治療藥物的選擇與使用上應更加地謹慎，以減低生態環境的衝擊與公共衛生上的疑慮。

關鍵字

抗菌劑 ； 感受性 ； 海水魚

並列摘要

The aim of this study was to investigate the antimicrobials susceptibility profile of 9 target bacteria which isolated from normal fish gill, intestine and water samples at twenty-five seawater fish farms in southern Taiwan. The selected target organisms included: Aeromonas spp., Vibrio spp., Pseudomonas spp., Escherichia coli, Pasteurella spp., Salmonella spp., Staphylococcus spp., Streptococcus spp. and Entercoccus spp.. The cultivation results suggest that the major bacteria species which isolated from mentioned sources were very similar. The disk diffusion results indicated that those isolates were highly resistant to sulfadiazine, sulfamethazine, amoxicillin, oxytetracycline and chloramphenicol. However, isolates were still sensitive to furazolidone, gentamicin and quinolones. Since most isolated bacteria already shown multiresistance to tested antimicrobials, authors suggest that regulating the usage of therapeutic agents in aquaculture to decreasing ecological impact and public health concerns.

並列關鍵字

Antimicrobials ； susceptibility ； seawater fish