臺灣慢性阻塞性肺疾病患者憂鬱症發生率之世代追蹤研究

The Incidence of Depression among Patients with COPD: A Nationwide Cohort Study in Taiwan

吳蕙屏(Hui-Ping Wu) ； 范國聖(Kuo-Sheng Fan) ； 蔡宗益(Tzung-Yi Tsai)

《志為護理-慈濟護理雜誌》 11卷6期 (2012/12) Pp. 66-75

https://doi.org/10.6974/TCNJ.201212.0066

摘要

此世代追蹤研究旨在探討台灣COPD患者之憂鬱症發生率。研究對象取自全民健康保險研究資料庫之2000年百萬承保抽樣歸人檔。以2000～2003年間被診斷為COPD者為研究世代，而後透過年齡與性別配對並以1：1方式，從其餘個案隨機篩選非COPD世代。所有研究對象皆追蹤至2008年，再以Cox比例危害模式估算憂鬱症罹病風險和95％信賴區間。兩世代各有32,170位個案納入分析，其中COPD世代之憂鬱症發生率為每千人年12.26，非COPD世代憂鬱症發生率則為每千人年6.96；易言之，COPD患者的確有較高的憂鬱症罹病風險，約為常人的1.60倍。建議宜將憂鬱症篩檢列為常規照護項目，以隨時掌握COPD病人治療期間的心理變化。

關鍵字

全民健康保險研究資料庫 ； 憂鬱症 ； 發生率 ； 慢性阻塞性肺病

並列摘要

The cohort study aimed to quantify the incidence of depression among COPD patients in Taiwan. All subjects were extracted from Longitudinal Health Insurance Database 2000, which was a subset of the National Health Insurance Research Database and contains all medical claims data for one million beneficiaries. The study cohort consisted of patients who had received a diagnosis of COPD from 2000 to 2003. Afterward, we randomly extracted a comparison cohort (one for every case in the study cohort) matched with those in the study cohort in terms of age and gender from the remaining cases. A total of 32,170 patients with COPD and 32,170 age- and sex-matched controls were recruited. We found the incidence rate of depression were 12.26 per 1000 person-years of follow-up in COPD cases and 6.96 per 1000 person-years in controls. In other words, COPD cases had a 1.60-fold increasing risk in depression as compared to general population. Therefore, routine screening for depression is urgently warranted to timely detect the mood level among COPD patients.

並列關鍵字

COPD ； depression ； incidence ； National Health Insurance Research Database