This study presented the nursing experiences of a moderate dementia patient complicated with postoperative enterocutaneous fistula. The nursing period lasted between May 21^(st) and June 20^(th), 2014. Gordon 11 functional health patterns were applied to assess patient's condition, and the following nursing problems were identified: impaired skin integrity, pain, nutritional imbalance, and helplessness in the primary caregiver. To accommodate these problems, the following nursing care were provided: reduce excrement leakage on the skins surrounding the fistula, facilitate comfort by employing low pressure suction and changing dressing methods; relief pain by approaching the patient's pain reaction with empathy and distract the patient's attention when dressing; reduce the wound and stabilize the condition by offering appropriate tube feeding diet and individualized health care to prepare for fistula closure; educate caregiver on difficult wound care and enhance the caregiver's life quality by providing emotional relief and support. The nursing experience can serve as a reference for nursing future patients with similar conditions.