This article described the nursing experience of an adult male with right hemiparesis that was caused by anti-phospholipid syndrome. The nursing period lasted from May 23^(th) to Jun. 13^(th), 2014. The author applied Gordon's 11 function health patterns as an assessment tool and collected data through medical records, conversation, physical assessment, and direct care. The health problems identified included self-care deficit, risk of falls, situational low self-esteem, and altered family process. To address theses health issues, during the nursing process, the author implemented the following nursing interventions: establish the patient's confidence through the company of the family members and the medical team; relief the anxiety of the patient's wife by providing relevant disease information, and maintain family integrity. The author hopes that this nursing experience could serve as a reference for clinical nurses to improve overall quality of care when tending to patients with similar conditions.