Sepsis is one of the main causes of death in acute and severe patients. Thus, immediate identification and proper care for sepsis are clinically necessary. The emergency department had 2,331 sepsis cases in 2017. Only 11 cases were treated within 3 hours of arrival at the hospital which may be because the standard operating procedures have not been established and integrated care was lacking. This case report aims to improve the timeliness and care awareness of the emergency sepsis process. The treatment time was up to 4 hours, 21min, 9sec, after investigation and analysis of the current situation. In addition, the correct rate of care awareness was only 62.9%. Thus, the medical team resource management was used to introduce cross-disciplinary cooperation, work specification mechanism, and team communication to achieve consensus, formulate standard operating procedures, promote the treatment time limit to within 3 hours, and improve the cognitive accuracy rate of care to 95%. Interdisciplinary Teamwork not only improves potential problems but also smoothly builds standard processes to shorten operation time, and ultimately improves the quality of patient-centered medical services and care.