Any omissions of charging medical materials can result in an increase in medical costs and even put patients' lives at risk. In this study, the omission rate for charging medical materials in one neurological intensive care unit was found to be 49.3%. In this report we conducted a literature review and matrix analysis of the relevant literature. The following improvement actions were then taken: establishing a standard operating procedure for charging medical materials on the information system; adding new functions for commonly used medical materials and reminders to the information system; drawing up an auditing and reward scheme; compiling a table listing the types and prices of medical materials; and providing on-the-job training for the information system. The use of an information system and QR codes innovated the perception of, and the solution to, charging medical materials. The result showed the omission rate for charging medical materials was reduced to 8.5% from 49.3% after the improvement actions. Not only did the omission rate for charging medical materials drop but nursing personnel also kept abreast of current technological developments.