不同劑量咖啡因對青少年血壓之影響

本研究探討不同劑量咖啡因對於青少年血壓之影響。方法：以19位健康高中男性青少年（平均年齡17.9±0.7歲，平均身高173.5±5.6公分，平均體重64.9±8.7公斤）於不同時間，靜止並維持坐姿接受0mg（安慰劑）、100 mg、200 mg及300 mg四種咖啡因劑量，並於咖啡因介入前與介入90分鐘後量測受試者的手臂動脈血壓值。結果：由分析結果得到，咖啡因攝取的劑量增加，受試者的收縮壓（由119±7 mmHg升至131±13 mmHg）雖有提升，但沒有顯著增加；而舒張壓（由65±8 mmHg升至73±8 mmHg）也有提升的趨勢，其中又以200 mg、300 mg咖啡因介入後，舒張壓平均上升4±7 mmHg最為顯著。結論：本實驗結果指出，咖啡因攝取與青少年血壓之提升有關，建議青少年在食用含有咖啡因含量的食物，建議以200 mg為上限。

關鍵字

咖啡因；血壓；青少年

並列摘要

OBJECTIVE: The purpose of this study was to exam the effect of the caffeine intake to the blood pressure among adolescents. METHOD: Different dosages of caffeine (0 mg, 100 mg, 200 mg, and 300 mg) were administered orally to 19 healthy senior high school volunteers (age: 17.9 ± 0.7 years; ht: 173.5 ± 5.6 cm; wt: 64.9 ± 8.7 kg). The blood pressures [systolic blood pressure (SBP) and diastolic blood pressure (DBP)] were measured before and 90 minutes after the caffeine intervention. RESULTS: Although SBP was not significantly affected by different dosages of caffeine, but it had a tendency of increasing SBP when the dosage of caffeine intake increased; DBP was positively and significantly (p＜0.05) affected by the different dosages of caffeine intake. After 200 mg, 300 mg caffeine intake, the DBP increased from 69±8 mm Hg to 73±6 mm Hg and 69±10 mm Hg to 73±8 mm Hg, respectively. CONCLUSIONS: Caffeine intake significantly increases DBP in healthy adolescents. Our finding suggested that the adolescents should not have to drink caffeine more than 200 mg daily.

並列關鍵字

Caffeine ； Blood pressure ； Adolescents

參考文獻

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