骨質疏鬆症相關危險因子與停經前女性骨質密度的關係

Relationship between Osteoporosis Related Risk Factors and Bone Mineral Density in Premenopausal Taiwanese Women

王梓軒(Tzu-Hsuan Wang) ； 趙婉純(Kuei-Yuan Ho) ； 侯貴圓(Zong-Ho Lan) ； 藍種禾(Xi-I Lai) ； 賴世育(Woan-Chwen Jaw) ； 王永成(Yong-Cheng Wang) ； 鄭慶明(Chin-Ming Jeng)

《中華放射線技術學雜誌》 31卷2期 (2007/12) Pp. 155-163

https://doi.org/10.30045/CJRT.200712.0010

摘要

The purpose of this study is to investigate the bone mineral density (BMD) among Taiwanese premenopausal women and to understand the relationship between BMD and a number of osteoporosis-related risk factors. A total of 72 females aged 20~44 years were enrolled in the study. BMD of lumbar spine and femur were assessed with dual-energy X-ray absorptiometry (DXA). Data was collected in the form of structured questionnaire including sociodemographic characteristics, parity, lactation, calcium intake, smoking status, alcohol intake and physical activity. We found there were no relationship between BMD and age, height, BMI, lactation, alcohol intake, smoking status and physical activity (p＞0.05). Body weight was positively correlated with BMD (r =0.28, p=0.02 及r=0.24, p=0.05). In multiple regression analysis, age, height, weight, BMI and lactation were not significantly associated with BMD. Significant association was observed among BMD of total hip and parity. In conclusion, numbers of parity would cause 2% bone loss of total hip in our study. Since BMD is an effective predictor of osteoporotic fractures, knowledge of the relationship between osteoporotic related risk factors and BMD is required for premenopausal women.

關鍵字

骨質疏鬆症 ； 雙能量X光骨質密度儀 ； 骨質密度 ； 停經前女性

並列摘要

The purpose of this study is to investigate the bone mineral density (BMD) among Taiwanese premenopausal women and to understand the relationship between BMD and a number of osteoporosis-related risk factors. A total of 72 females aged 20~44 years were enrolled in the study. BMD of lumbar spine and femur were assessed with dual-energy X-ray absorptiometry (DXA). Data was collected in the form of structured questionnaire including sociodemographic characteristics, parity, lactation, calcium intake, smoking status, alcohol intake and physical activity. We found there were no relationship between BMD and age, height, BMI, lactation, alcohol intake, smoking status and physical activity (p＞0.05). Body weight was positively correlated with BMD (r =0.28, p=0.02 及r=0.24, p=0.05). In multiple regression analysis, age, height, weight, BMI and lactation were not significantly associated with BMD. Significant association was observed among BMD of total hip and parity. In conclusion, numbers of parity would cause 2% bone loss of total hip in our study. Since BMD is an effective predictor of osteoporotic fractures, knowledge of the relationship between osteoporotic related risk factors and BMD is required for premenopausal women.

並列關鍵字

osteoporosis ； dual-energy X-ray absorptiometry ； bone mineral density ； premenopausal women