以磁振造影技術檢視台灣兒童腦下垂體體積評估性早熟之關係

The Relationship Study of Pituitary Gland Volume and Sexual Precocity in Taiwan Children by Magnetic Resonance Imaging

杜俊元(Chen-Yuan Tu) ； 林鼎裕(Tin-Yu Lin) ； 黃武達(Wu-Dar Huang) ； 黃榮貴(Jon-Kway Huang) ； 楊斐適(Fei-Shish Yang) ； 莊奇容(Chi-Long Juang)

《中華放射線技術學雜誌》 34卷1期 (2010/03) Pp. 15-20

https://doi.org/10.30045/CJRT.201003.0003

摘要

The non-invasive magnetic resonance imaging method was employed to measure the pituitary volumes of children in Taiwan area. From our study, the comparison exterior between normal with exceptional pituitary gland in Taiwan area could be built. Furthermore, the information could also be provided as the reference of clinical diagnosis in pediatrics department. Children under the age of 14 and undergoing brain MRI for endocrines development disease or for other diagnostic purpose were our major subjects. Sixty-three children were eligible (mean age, 5.8 years). Forty images were collected by modern MRI Spoiled Gradient-recalled Acquisition in the Steady-state technique for each subject. Direct pituitary volumes were then measured after multi-plane reconstruction for each image. In total, forty images of axial and forty images of saggittal plane were reconstructed separately for each subject. In order to improve the accuracy and avoid errors, the area of each image was measured six times and then the average value was calculated. Finally, the volume of each plane was obtained by summarizing all averaged images of that plane. Our results indicated that the average volumes 547.45±146.48 mm^3 of sexual precocity children were higher than normal children 282.14±125.13 mm^3 (P＜0.05), which had statistically significance. The average volumes of development delay children were smaller than normal children (P＞0.05), however did not have statistically significance.

關鍵字

腦下垂體體積 ； 磁振造影 ； 消除穩定態之梯度重聚擷取 ； 性早熟

並列摘要

The non-invasive magnetic resonance imaging method was employed to measure the pituitary volumes of children in Taiwan area. From our study, the comparison exterior between normal with exceptional pituitary gland in Taiwan area could be built. Furthermore, the information could also be provided as the reference of clinical diagnosis in pediatrics department. Children under the age of 14 and undergoing brain MRI for endocrines development disease or for other diagnostic purpose were our major subjects. Sixty-three children were eligible (mean age, 5.8 years). Forty images were collected by modern MRI Spoiled Gradient-recalled Acquisition in the Steady-state technique for each subject. Direct pituitary volumes were then measured after multi-plane reconstruction for each image. In total, forty images of axial and forty images of saggittal plane were reconstructed separately for each subject. In order to improve the accuracy and avoid errors, the area of each image was measured six times and then the average value was calculated. Finally, the volume of each plane was obtained by summarizing all averaged images of that plane. Our results indicated that the average volumes 547.45±146.48 mm^3 of sexual precocity children were higher than normal children 282.14±125.13 mm^3 (P＜0.05), which had statistically significance. The average volumes of development delay children were smaller than normal children (P＞0.05), however did not have statistically significance.

並列關鍵字

pituitary volumes ； Magnetic Resonance Imaging ； Spoiled Gradient-recalled Acquisition in the Steady-state SPGR ； Sexual Precocity