低劑量電腦斷層攝影於冠狀動脈鈣化與年齡及抽煙之依賴性評估

Low Dose Computed Tomography Evaluating the Dependent Relationship of Coronary Arterial Calcification to Age and Smoking

吳宗原(Tsung-Yuan Wu) ； 張潤忠(Yun-Chung Cheung) ； 蔡熒煌(Ying-Huang Tsai)

《中華放射線技術學雜誌》 34卷1期 (2010/03) Pp. 29-34

https://doi.org/10.30045/CJRT.201003.0005

摘要

The purpose of this study aims at the patients after receiving the low dose multi-detectors computed tomography (LD-MDCT) of lung to analyze the coronary artery calcification (CAC) relating to the gender, age, smoking with the coronary artery calcification relevance. From the data of LD-MDCT of lung between 2007 Aug. to 2008 Dec., we selectively analyzed 655 participants who did not have heart disease history or cardiac discomfort. In the male non-smokers, the prevalence of CAC in ages less than 50, between 50 to 59, between 60 to 69 and greater than 69 were to 11.63%, 36.36%, 57.14% and 71.43%, as well as the average calcium scores to 0.37, 34.76, 55.35 and 231.68 respectively. The female non-smokers had the same result. On the other hand, the incidence and degree of calcifications were directly increased with the patient's ages, revealing statistic significance in the CAC scores (P＜0.001). In comparing the smokers and non-smokers, the incidences of CAC were 37.22% for non-smokers and 49.28% for smokers. The prevalence of CAC of the smoker was higher than non-smoker (averagely 104, 31 VS 67.46, P=0.109). Otherwise, the CAC was directly proportion to the smoking duration with the results of 22.5% for 19 years, 44.9% for 20 to 39 years, 70.69% for over 39 years, as well to the CAC scores 24.49, 64.00 and 225.89 respectively (P＜0.001 in both). Conclusively, the ungated low-dose MDCT of lung, not only for lung examination, but also can be derived the extra-understanding coronary artery calcification degree. This information can contribute to risk stratification and management of coronary artery disease.

關鍵字

低劑量電腦斷層LDCT ； 冠狀動脈鈣化CAC ； 抽煙

並列摘要

The purpose of this study aims at the patients after receiving the low dose multi-detectors computed tomography (LD-MDCT) of lung to analyze the coronary artery calcification (CAC) relating to the gender, age, smoking with the coronary artery calcification relevance. From the data of LD-MDCT of lung between 2007 Aug. to 2008 Dec., we selectively analyzed 655 participants who did not have heart disease history or cardiac discomfort. In the male non-smokers, the prevalence of CAC in ages less than 50, between 50 to 59, between 60 to 69 and greater than 69 were to 11.63%, 36.36%, 57.14% and 71.43%, as well as the average calcium scores to 0.37, 34.76, 55.35 and 231.68 respectively. The female non-smokers had the same result. On the other hand, the incidence and degree of calcifications were directly increased with the patient's ages, revealing statistic significance in the CAC scores (P＜0.001). In comparing the smokers and non-smokers, the incidences of CAC were 37.22% for non-smokers and 49.28% for smokers. The prevalence of CAC of the smoker was higher than non-smoker (averagely 104, 31 VS 67.46, P=0.109). Otherwise, the CAC was directly proportion to the smoking duration with the results of 22.5% for 19 years, 44.9% for 20 to 39 years, 70.69% for over 39 years, as well to the CAC scores 24.49, 64.00 and 225.89 respectively (P＜0.001 in both). Conclusively, the ungated low-dose MDCT of lung, not only for lung examination, but also can be derived the extra-understanding coronary artery calcification degree. This information can contribute to risk stratification and management of coronary artery disease.

並列關鍵字

Low Dose Computed Tomography LDCT ； Coronary Artery Calcification CAC ； Smoking