- 期刊
A Technical Note of 131I-6β-iodomethyl-19-norcholesterol SPECT/CT for Adrenal Cortical Imaging: Short Communication
碘－131 NP-59 SPECT/CT於腎上腺皮質掃描之技術報告：短論
摘要
腎上腺皮質掃描(NP-59 scintigraphy)可評估腎上腺皮質功能。通常，於靜脈注射NP-59後第3、4、5天取得平面影像。因平面影像解析度不佳，對於小病灶的偵測可能會有限制；使用單光子電腦斷層技術，可明顯提高腎上腺皮質掃描影像解析度。然而，一些生理上攝取（肝、膽道、膽囊和腸胃道）亦可能被認為腎上腺皮質功能亢進而導致錯誤判讀。藉由核醫腎上腺功能性檢查從平面影像到單光子電腦斷層檢查可提供腎上腺病理及生理資訊。新的NP-59 SPECT/CT藉由電腦斷層影像檢查提供病灶高解析度及準確解剖定位顯示核醫檢查在腎上腺腫瘤的評估中扮演非常重要的角色。
並列摘要
131I-6β-iodomethyl-19-norcholesterol (NP-59) scintigraphy can assess the functioning of the adrenal cortex. Routinely, planar images are acquired on days 3, 4, and 5 after NP-59 injection. Because of the resolution limit of planar imaging may prevent the detection of small lesions. Use SPECT technology for NP-59 scintigraphy improves the resolution of images significantly. However, some physical uptakes (hepatic, biliary, gallbladder, and gastrointestinal) may caused misinterpreted as hyper-functioning adrenal gland. Use adrenal functional imaging from planar scintigraphy to SPECT depicted adrenal path-physiology. New NP-59 SPECT/CT offers the opportunity with high resolution and lesion anatomical localization derived from CT imaging. It demonstrates nuclear medicine studies play an integral role in adrenal tumor evaluation.
延伸閱讀
- Huang, Y. E., Wang, P. W., Huang, H. H., Chen, W. J., Hsu, Y. H., Wu, Y. C., & Lee, C. H. (2001). 碘—131—NP—59腎上腺造影對於ACTH—非依賴性庫欣氏癥候群之角色. 核子醫學雜誌, 14(2), 75-83. https://doi.org/10.6332/ANMS.1402.002
- 吳杰、張柏菁、張淑君、莊濬超、莊克士、陳英鑒、邱志宏（2003）。參考人假體與個人混合型假體應用於碘-131甲狀腺體內劑量評估之比較。核子醫學雜誌，16(4)，203-210。https://doi.org/10.6332/ANMS.1604.008
- Kao, C. H., Liao, S. Q., Wang, S. J., Lin, M. S., Hsu, C. Y., & Lin, W. Y. (1992). 以I-131 NP-59腎上腺皮質閃爍造影術評估疑似原發性醛類酯過多症. The Kaohsiung Journal of Medical Sciences, 8(4), 213-218. https://doi.org/10.6452/KJMS.199204.0213
- 路景竹（2011）。斷層掃描與核子醫學腎上腺掃描於原發性皮質醛酮症之成本效果分析〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2011.01065
- 黃政凱、蔡世傳、黃華思、鄭凱元（2005）。核醫NP-59腎上腺皮質檢查配合電腦斷層用以診斷庫辛症候群－病例報告。中華放射線技術學雜誌，29(2)，195-199。https://doi.org/10.30045/CJRT.200512.0011