利用影像導引放射治療評估具有侵入管路的頭頸部患者擺位準確性

Use of Image-guided Radiation Therapy to Evaluate Setup Accuracy with Invasive Tubes of the Head and Neck Patients

康誠麟(Chen-Lin Kang) ； 王瑞祝(Jui-Chu Wang) ； 張力允(Li-Yun Chang) ； 陳懷哲(Huai-Che Chen) ； 陳文凱(Wen-Kai Chen) ； 廖宗義(Tzung-Yi Liao) ； 阮國榮(Kuo-Jung Juan)

《中華放射線技術學雜誌》 37卷3期 (2013/09) Pp. 133-138

摘要

In the process of radiation therapy, the set-up error is the key factor affect the precision. Higher treatment accuracy is required for more precise radiation therapy. This study was designed to evaluate the positioning accuracy of the head and neck patients with invasive tubes which use cone-beam computed tomography (CBCT) in radiation therapy. We collected seventy-two patients received image-guided radiotherapy (IGRT) to analyze the setup data. The seventy-two patients were divided into four groups in this study. In the Group A of seven patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 1.92±0.10 mm, 1.68±0.06 mm, and 2.11±0.09 mm. And that of random errors were 2.04±0.25 mm, 0.88±0.02 mm, and 1.04±0.05 mm, respectively. In the Group B of twelve patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 2.17±0.13 mm, 1.70±0.06 mm, and 1.30±0.03 mm. And that of random errors were 1.02±0.03 mm, 0.93±0.03 mm, and 0.80±0.02 mm, respectively. In the Group C of twenty-seven patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 1.92±0.10 mm, 1.61±0.10 mm, and 1.63±0.10 mm. And that of random errors were 0.89±0.03 mm, 0.84±0.04 mm, and 0.76±0.04 mm, respectively. In the Group D of twenty-six patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 1.13±0.04 mm, 1.30±0.06 mm, and 1.92±0.10 mm. And that of random errors were 0.61±0.02 mm, 0.67±0.02 mm, and 0.65±0.03 mm, respectively. Using One-way ANOVA analysis of the systematic errors, we found the statistically significant difference (p＜0.05) in X (L-R) and Z (A-P) direction(p = 0.003 and 0.008). And that of the statistically significant difference (p ＜0.05) of random errors only in X (L-R) direction (p = 0.001). Finally, we hope to use the retrospective study which result can be a clinical treatment reference, and provide better accuracy in treatment positioning, effectively improve and enhance the quality of radiotherapy.

關鍵字

固定器 ； 錐狀射束電腦斷層 ； 影像導引放射治療

並列摘要

In the process of radiation therapy, the set-up error is the key factor affect the precision. Higher treatment accuracy is required for more precise radiation therapy. This study was designed to evaluate the positioning accuracy of the head and neck patients with invasive tubes which use cone-beam computed tomography (CBCT) in radiation therapy. We collected seventy-two patients received image-guided radiotherapy (IGRT) to analyze the setup data. The seventy-two patients were divided into four groups in this study. In the Group A of seven patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 1.92±0.10 mm, 1.68±0.06 mm, and 2.11±0.09 mm. And that of random errors were 2.04±0.25 mm, 0.88±0.02 mm, and 1.04±0.05 mm, respectively. In the Group B of twelve patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 2.17±0.13 mm, 1.70±0.06 mm, and 1.30±0.03 mm. And that of random errors were 1.02±0.03 mm, 0.93±0.03 mm, and 0.80±0.02 mm, respectively. In the Group C of twenty-seven patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 1.92±0.10 mm, 1.61±0.10 mm, and 1.63±0.10 mm. And that of random errors were 0.89±0.03 mm, 0.84±0.04 mm, and 0.76±0.04 mm, respectively. In the Group D of twenty-six patients: The mean translation and standard deviation of systematic errors in X(L-R), Y(S-I), Z(A-P) were 1.13±0.04 mm, 1.30±0.06 mm, and 1.92±0.10 mm. And that of random errors were 0.61±0.02 mm, 0.67±0.02 mm, and 0.65±0.03 mm, respectively. Using One-way ANOVA analysis of the systematic errors, we found the statistically significant difference (p＜0.05) in X (L-R) and Z (A-P) direction(p = 0.003 and 0.008). And that of the statistically significant difference (p ＜0.05) of random errors only in X (L-R) direction (p = 0.001). Finally, we hope to use the retrospective study which result can be a clinical treatment reference, and provide better accuracy in treatment positioning, effectively improve and enhance the quality of radiotherapy.

並列關鍵字

fixation device ； cone-beam computed tomography ； image-guided radiotherapy