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SPECT/CT Using Gallium-67 Inflammatory Scintigraphy for Diagnosis of Acute Pyelonephritis: A Case Report

使用鎵-67光子電腦斷層炎症造影於急性腎盂腎炎之輔助診斷:病例報告

摘要


急性腎盂腎炎主要由細菌的感染產生急性發炎,細菌可能經由尿道、膀胱侵入輸尿管擴散到腎臟而引起的感染而導致腎小管間質炎症。鎵-67炎症造影己廣泛使用在疑似感染之評估,然而,鎵-67炎症造影會因較低的空間分辨率和缺乏解剖定在臨床上判讀上受到限制。光子電腦斷層能將核醫功能性影像和電腦斷層解剖影像做精確影像融合,其影像融合結果已被證實在評估感染或腫瘤評估有助益。一位不明原因發熱的患者,安排鎵-67炎症造影,藉此尋找膿腫位置,鎵-67炎症造影發現在患者左腹部有顯著示踪劑攝取;藉由光子電腦斷層精確地定位鎵-67示踪劑攝取位左腎上半部,綜合鎵-67炎症造影與鎵-67光子電腦斷層影像融合發現,患者左腎上部位鎵-67示踪劑攝取被認為是急性腎盂腎炎及腎週膿腫所引起。

並列摘要


Acute pyelonephritis (APN) primarily results from bacterial infection of the kidney by an ascending route that causes a tubulointerstitial inflammation of the renal parenchyma. Gallium-67 (Ga-67) scintigraphy (GS) has been widely used in the assessment of suspected infection .But, GS may be limited because relatively low spatial resolution and the lack of anatomic landmarks of scintigraphy. A SPECT/CT device that provides accurate online spatial fusion of functional and anatomic imaging data has been shown to be beneficial for the evaluation of infection and tumors. A patient with fever of unknown origin underwent GS in search of an occult abscess. GS shows an area of significantly increased tracer uptake in the left abdomen. SPECT/CT can precisely localizing Ga-67 uptake involving upper pole of left kidney. Combined GS and SPECT/CT using Ga-67 findings, APN and perirenal abscess are considered involving upper portions of left kidney.

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