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乳房惡性腫瘤與良性病灶在超音速剪力波彈力量化圖上的比較

Quantitative Supersonic Shear Imaging Elastography on Benign and Malignant Breast Lesion

摘要


利用超音速剪力波彈力圖(supersonic shear imaging;SSI)獲得良性病灶與惡性腫瘤之間的彈性數值差異,並分別將其內外周圍的彈性量化數值做比較,進一步與病理切片做相關性分析。觀察BI-RADS US(The Breast Imaging Recording and Diagnostic System Ultrasound)在傳統超音波與SSI影像數值上的分類變化。本研究共收錄了12位婦女,利用Aixplorer ultrasound system(Supersonic Imagine,Aix en provence,France)機器來做SSI數值檢測,並在病灶影像最大切面內外各選取2個以上感興趣區(regions of interest;ROI)做測量。良性病灶SSI最大彈性數值與惡性腫瘤SSI最大彈性數值(38.03±19.50;137.24±75.82 p=0.004)達統計上差異。BI-RADS US分級上變化有8位。由本研究得知SSI可以提供有效的組織彈性量化值,此技術可以配合灰階與彩色杜卜勒超音波來增加乳房腫瘤診斷率並降低對良性病灶做切片檢查。

並列摘要


The aims of this study were to compare the elasticity between benign and malignant breast lesions and to correlate the elasticity values of breast masses with histopathologic findings. We analyzed the elasticity of the tissue surrounding the mass and inside of a malignant lesion. The BI-RADS US (Breast Imaging-Recording and Diagnostic System Ultrasound) category based on conventional gray-scale ultrasound and information obtained from supersonic shear imaging (SSI) were document. The ultrasonic investigation was performed in 12 patients using the Aixplorer Ultrasound System(Supersonic Imagine, Aix en provence, France)to obtain the elasticity value with a property selected ROI. The maximum elasticity between benign and malignant lesions had significant difference (38.03±19.50 kPa vs 137.24±75.82 kPa, p=0.004). There are 8 subjects showed change in BI-RADS US category. We concluded that SSI can provide the quantitative elasticity of breast masses and can improve the diagnostic accuracy with reduce biopsy in benign lesion.

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