磁振造影可提供肝臟惡性腫瘤較好的診斷效果,然而,並非所有病患都能夠配合閉氣來完成造影。本研究目的是以呼吸導航(navigated)來協助無法配合閉氣的病人來完成三維T1 加權梯度回波序列,採用回溯型研究,自 2014 年1 月1 日至2016 年5 月31 日,收集其中皆包含顯影後閉氣三維T1 加權梯度回波軸切面影像及顯影後呼吸導航三維T1 加權梯度回波軸切面影像,共24 位病患,分別在肝臟的第四、六及第七葉相對應處,計算對比雜訊比。另將影像由兩位放射科主治醫師針對解剖結構及假影表現進行影像品質評分,使用五級分法。結果顯示,在對比雜訊比方面,呼吸導航組為23.6±7.30 優於閉氣組的17.0±4.70(p<0.001);在影像品質方面,呼吸導航影像為4.20±0.97,閉氣影像為2.17±0.83(p<0.001)。因此,在三維T1 加權梯度回波序列上,呼吸導航應用在無法配合閉氣的病患上,提供了更好的對比雜訊比及影像品質。
Magnetic resonance imaging (MRI) has emerged as a useful diagnostic tool for liver cancer. However, not all the patients can cooperate to hold their breaths during the MRI scan. The purpose of the study is to evaluate whether the respiration navigated 3D T1 gradient sequence (liver acquisition with volume acceleration-flexible, navigated LAVA-Flex) can be used in patients who cannot temporarily hold their breaths completely. Twenty-four patients underwent liver MRI study, the LAVA-Flex sequence was acquired using both the navigated and breath-holding techniques. The contrast-to-noise ratio (CNR) at segment 4, 6 and 7 of the liver were measured. Two radiologists compared the image quality of the acquired images using a 5-point scale. The CNR and image quality of the images acquired using the navigated method were significantly higher than those acquired using breath-holding method (CNR: 23.6±7.30 vs. 17.0±4.70, p<0.01; image quality: 4.20±0.97 vs. 2.17±0.83, p<0.01). Therefore, the navigated LAVA-Flex sequence can be used as a substitute in abdominal MRI for patients who cannot hold their breaths.