心臟冠狀動脈電腦斷層血管攝影檢查之輻射劑量與輻射風險評估

本研究提供320切前瞻性心電閘控掃描技術心臟冠狀動脈電腦斷層血管攝影之平均有效劑量與輻射風險，使用多種趨近於人體實際解剖特性的人形混合性模型之VirtualDose劑量模擬軟體計算有效劑量，並搭配PCXMC軟體計算輻射風險，其收集68位受檢者，受檢者器官劑量最高者為女性之乳腺（35.1±12.0 mGy），男性與女性平均有效劑量為11.4±1.6和12.4±4.5 mSv，有效劑量無顯著差異（p = 0.204），而使用胸部劑量轉換因子（k = 0.014）計算有效劑量約低估46%。其中受檢者年齡與有效劑量較無顯著關係（p = 0.71），而有效劑量對於受檢者身體質量指數、劑量長度乘積呈現顯著關係（p < 0.05）。男性與女性平均曝露導致罹癌死亡風險每百萬人分別為277和545人，女性相較於男性高，男性與女性年齡與曝露導致罹癌死亡風險有顯著關係（p < 0.05），且隨年齡上升，曝露導致死亡風險下降。

關鍵字

冠狀動脈電腦斷層血管攝影；器官劑量；有效劑量；輻射風險

並列摘要

This study provides the mean effective dose and radiation risk of CCTA with 320 slice prospective ECG-triggering. The Virtual Dose software is used to calculate effective dose for different body size of male and female, and PCXMC software is used to calculate radiation risk. We collected 68 cases who used CCTA. The highest organ dose was the female breast (35.1±12.0 mGy). The mean effective dose in the women was qual to than that in the men (11.4±1.6 vs 12.4±4.5 mSv, p = 0.204). The chest k-factor (0.014 mSv．mGy^(-1)cm^(-1)) underestimates effective dose by an average of 46%. The effective doses were independent of patient age (p = 0.71). The effective doses were dependent of patient BMI and dose length product (p < 0.05).The mean risk of exposure-induced death (REID) values in patients undergoing CCTA with a 320 scanner were 277 per 1,000,000 men and 545 per 1,000,000 women. The REID values were considerably higher for the younger women. The REID were dependent of patient age (p < 0.05).The REID will decline as age increases.

並列關鍵字

coronary computed tomography angiography ； organ dose ； effective dose ； radiation risk

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