Prognostic Value of Oophrectomy in Colorectal Cancer Patients with Ovarian Metastasis

結腸直腸癌併卵巢轉移的病人接受卵巢切除手術治療的預後

林春吉(Chun-Chi Lin) ； 林楨國(Jen-Kou Lin) ； 張世慶(Shih-Ching Chang) ； 王煥昇(Huann-Sheng Wang) ； 楊純豪(Shung-Haur Yang) ； 姜正愷(Jeng-Kai Jiang) ； 陳維熊(Wei-Shone Chen) ； 林資琛(Tzu-Chen Lin)

《中華民國大腸直腸外科醫學會雜誌》 20卷4期 (2009/12) Pp. 94-99

https://doi.org/10.6312/SCRSTW.2009.20(4).09813

摘要

目的　結腸直腸癌女性病患約百分之3~8會發生卵巢轉移。根除性卵巢切除已被報告可以增加病人整體存活率。此篇研究是爲了研究本院針對結腸直腸癌併卵巢轉移的病人手術治療的預後。
方法　從2001年三月到2005年十月共有32位結腸直腸癌病人在本院接受卵巢切除手術。這些病人的臨床及病理的資料與預後的關係將予以分析。
結果　這些病人的追踪時間中位數爲32.6個月。單純只有卵巢轉移的病人有8位，這類病人有較好的預後，但未達顯著差異。不過，如果是轉移的病灶只發生在骨盆腔或是病人可以接受完全根除性手術，則明顯有較好的預後。
結論　結腸直腸癌併卵巢轉移病人如果轉移的病灶只發生在骨盆腔比轉移超過骨盆腔的病人有較好的預後。根除性手術對結腸直腸癌併卵巢轉移的病人是有效的，甚至可能有長期存活的可能。

關鍵字

結腸直腸癌 ； 卵巢轉移 ； 卵巢切除手術

並列摘要

Purpose. Ovarian metastasis was reported to occur in 3~8% female colorectal cancer patients. Improved overall survival has been reported of oophrectomy with curative intend. This study is aimed to investigate the prognosis of surgical treatment for ovarian metastasis from colorectal cancer in our institute.
Methods. Between March 2001 and October 2005, 32 patients receiving oophrectomy due to metastasis from colorectal cancer in VGHTPE were retrieved. The clinicopathologic data and prognosis were analyzed.
Results. The median follow-up duration was 32.6 months (7~72 months). Isolated ovarian metastasis, diagnosed in 8 patients, has a trend toward improved overall survival (p=0.128). Metastatic lesions confined in pelvis and curative operation were associated with improved overall survival significantly (p=0.028 and 0.027 respectively).
Conclusion. Patient who received surgery for ovarian metastases with disease confined to pelvis has better survival than who has associated extrapelvic metastases. Curative resection for ovarian metastasis is effective and could offer potential long-term survival.

並列關鍵字

Colorectal cancer ； Ovarian metastasis ； Oophrectomy