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Lactic Acidosis and Acute Renal Failure after Oral Sodium Phosphate for Bowel Preparation in a Diabetic Patient Using Metformin-A Case Report

一使用滅糖敏錠的糖尿病患在服用口服磷酸鈉清腸後發生乳酸中毒及急性腎衰竭-病例報告

摘要


以口服磷酸鈉作為大腸鏡檢前的清腸準備已經被廣泛使用多年。然而,其使用上的安全性,特別是針對腎功能的傷害逐漸引起關注。我們報告一位使用滅糖敏錠 (metformin)為降血糖藥的糖尿病患者,在服用口服磷酸鈉作為大腸鏡檢前的清腸後,出現乳酸中毒及急性腎衰竭的狀況。雖經緊急血液透析後康復,此兩種藥物併用的安全性仍值得我們多加注意。

並列摘要


Oral sodium phosphate (OSP) for bowel preparation before colonoscopy has been widely prescribed for many years. However, its safety, especially the possible renal damage, gradually raised concern in recent years. Here, we report a diabetic patient on metformin, developing lactic acidosis and acute renal failure after taking OSP for colonoscopy. This patient recovered after emergency hemodialysis. OSPbowel cleansing may be contraindicated in patients on metformin for diabetes mellitus.

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