Origin of Metastatic Colonic Adenocarcinoma Suspected from a Primary Lung Cancer: A Case Report and Literature Review

疑似來自原發肺腺癌之大腸轉移：病例報告及文獻回顧

王景賢(Ching-Hsien Wang) ； 金仁(Jen Chin) ； 錢尚道(Shang-Tao Chien) ； 陳仁智(Jen-Chih Chen) ； 陳東源(Tung-Yuan Chen) ； 吳岳嶸(Yueh-Jung Wu) ； 王貫宇(Kuan-Yu Wang)

《中華民國大腸直腸外科醫學會雜誌》 26卷1期 (2015/03) Pp. 38-43

https://doi.org/10.6312/SCRSTW.2015.26(1).10327

摘要

肺癌合併腸胃道轉移並不常見，在文獻記載中最常轉移的腸胃道部位是小腸，而只有少數肺腺癌病例轉移至大腸的文獻報導。我們報告一個以免疫組織化學染色法而高度懷疑原發於肺部腺癌且轉移至大腸合併腸阻塞及水氣胸的六十七歲女性。免疫組織化學染色證實thyroid transcription factor-1和cytokeratin 7在癌細胞裡面，及cytokeratin 20並未表現於癌細胞。我們同時回顧了以免疫組織化學染色來診斷癌症原發位置之文章及其他相關的發表文獻。

關鍵字

腺癌 ； 肺 ； 大腸 ； 轉移 ； 免疫組織化學

並列摘要

Lung cancer with gastrointestinal metastasis is uncommon; however, when such metastasis occurs, the small bowel is the most common metastatic site. There are few case reports of colonic metastasis developing from a primary lung adenocarcinoma. We report a case of metastatic adenocarcinoma in the colon, complicated by bowel obstruction and hydropneumothorax, in a 67-year-old woman. The primary cancer was highly suspected to have originated from the lung, based on immunohistochemistry assessments. Immunohistochemistry was positive for thyroid transcription factor-1 and cytokeratin 7, but negative for cytokeratin 20. The published literature, focusing on the differential diagnosis of the origin of the primary malignancy using immunohistochemistry, was reviewed.

並列關鍵字

Adenocarcinoma ； Lung ； Colon ； Metastasis ； Immunohistochemistry

參考文獻

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