某醫學中心普通病房及加護中心金黃色葡萄球菌醫療照護相關感染之調查分析

Analysis of Healthcare-associated Staphylococcus aureus Infections in General Wards and Intensive Care Units in a Medical Center

黃子鳳(Tzu-Feng Huang) ； 詹明錦(Ming-Chin Chan) ； 張靜美(Ching-Mei Chang) ； 邱玉惠(Yu-Hui Qiu) ； 張淑美(Shu-Mei Chang) ； 謝依潔(Yi-Jie Xie) ； 王甯祺(Ning-Chi Wang)

《感染控制雜誌》 21卷2期 (2011/04) Pp. 73-82

https://doi.org/10.6526/ICJ.201104_21(2).0001

摘要

Staphylococcus aureus has become one of the leading causes of healthcare-associated infections (HAIs) and has been responsible for increasingly severe diseases in recent years. This study analyzed S. aureus-related HAIs in general wards and intensive care units (ICUs) in a medical center located in northern Taiwan from 2004 to 2008. We evaluated the total S. aureus infection rate, overall density of infection, density by infection site, characteristics of infected patients, and risk factors for HAI. The results showed that the mean rates of S. aureus infection in general wards and ICUs in the 5-year study period were 0.38% and 0.97%, respectively. The most frequent site of infection, in both general wards and ICUs, was the bloodstream. There were no significant differences in sex or age of the infected patients. Patients in ICUs had significantly higher rates of cardiovascular diseases and diabetes, and a larger number of ICU patients were bedridden for a long time (p＜0.05). The frequency of invasive medical procedures, including peripheral and central venous catheterization, endotracheal intubation, tracheotomy, urinary catheterization, ventilator support, and total parenteral nutrition (p＜0.0001), in ICU patients was also higher. Since S. aureus can be transmitted from the hands of healthcare workers, the most effective method to control S. aureus infection is to follow standard aseptic procedures while performing medical procedures, especially during invasive catheterization. Strict adherence to hand hygiene is also recommended. Removal of catheters as early as possible and controlled use of antibiotics are also important factors for containing S. aureus-related HAIs.

關鍵字

金黃色葡萄球菌 ； 普通病房 ； 加護中心 ； 醫療照護相關感染

並列摘要

Staphylococcus aureus has become one of the leading causes of healthcare-associated infections (HAIs) and has been responsible for increasingly severe diseases in recent years. This study analyzed S. aureus-related HAIs in general wards and intensive care units (ICUs) in a medical center located in northern Taiwan from 2004 to 2008. We evaluated the total S. aureus infection rate, overall density of infection, density by infection site, characteristics of infected patients, and risk factors for HAI. The results showed that the mean rates of S. aureus infection in general wards and ICUs in the 5-year study period were 0.38% and 0.97%, respectively. The most frequent site of infection, in both general wards and ICUs, was the bloodstream. There were no significant differences in sex or age of the infected patients. Patients in ICUs had significantly higher rates of cardiovascular diseases and diabetes, and a larger number of ICU patients were bedridden for a long time (p＜0.05). The frequency of invasive medical procedures, including peripheral and central venous catheterization, endotracheal intubation, tracheotomy, urinary catheterization, ventilator support, and total parenteral nutrition (p＜0.0001), in ICU patients was also higher. Since S. aureus can be transmitted from the hands of healthcare workers, the most effective method to control S. aureus infection is to follow standard aseptic procedures while performing medical procedures, especially during invasive catheterization. Strict adherence to hand hygiene is also recommended. Removal of catheters as early as possible and controlled use of antibiotics are also important factors for containing S. aureus-related HAIs.

並列關鍵字

Staphylococcus aureus ； general ward ； intensive care unit ； healthcare-associated infection