茄紅素對小鼠體內抗氧化狀態之影響

Effect of Lycopene on Antioxidative Status in Mice

王銘富(Ming-Fu Wang) ； 許雯瑛(Wen-Ying Hsu) ； 詹吟菁(Yin-Ching Chan)

《美容科技學刊》 2卷2期 (2005/08) Pp. 139-147

https://doi.org/10.30001/JIES.200508.0010

摘要

Lycopene was demonstrated to has antioxidant capacity. The purpose et this study was to investigate the effect of lycopene on antioxidative status in mice. Six-month-old senescence accelerated male mice were divided into four groups: control group、4、20、100 ppm lycopene (experimental group). After 12 weeks of feeding, body weight, food intake, drink amount were performed during the experiment. The activity of superoxide dismutase (SOD), catalase and malondialdehyde (MDA), total thiol concentrations in the liver were analyzed after sacrificed. The results showed that there were no significant differences in the body weight, food intake were no significantly among four groups. The drink amount of experimental groups were higher than the control group (p＜0.05). The SOD activity of liver, 20、100 ppm lycopene groups were significantly higher than control group (p＜0.05). The liver catalase activity of 20 ppm lycopene group was significantly higher than control group (p＜0.05). The MDA concentrations of liver in the 20、100 ppm lycopene groups were significantly lower than control group. From the findings of these results, the supply of lycopene may improve antioxidative system on liver in SAMP8 mice.

關鍵字

茄紅素 ； 抗氧化 ； 老化促進小鼠

並列摘要

Lycopene was demonstrated to has antioxidant capacity. The purpose et this study was to investigate the effect of lycopene on antioxidative status in mice. Six-month-old senescence accelerated male mice were divided into four groups: control group、4、20、100 ppm lycopene (experimental group). After 12 weeks of feeding, body weight, food intake, drink amount were performed during the experiment. The activity of superoxide dismutase (SOD), catalase and malondialdehyde (MDA), total thiol concentrations in the liver were analyzed after sacrificed. The results showed that there were no significant differences in the body weight, food intake were no significantly among four groups. The drink amount of experimental groups were higher than the control group (p＜0.05). The SOD activity of liver, 20、100 ppm lycopene groups were significantly higher than control group (p＜0.05). The liver catalase activity of 20 ppm lycopene group was significantly higher than control group (p＜0.05). The MDA concentrations of liver in the 20、100 ppm lycopene groups were significantly lower than control group. From the findings of these results, the supply of lycopene may improve antioxidative system on liver in SAMP8 mice.

並列關鍵字

lycopene ； antioxidation ； senescence accelerated mice SAMP8

參考文獻

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