Non-Enteropathic Hemolytic-Uremic Syndrome after Herb Intake-A Case Report

服用草藥後發生溶血性尿毒症後群－一病例報告

陳怡安(Yi-Ann Chen) ； 馮祥華(Shyang-Hwa Ferng) ； 曾嶔元(Chin-Yuan Tzen) ； 楊垂勳(Chwei-Shiun Yang)

《輔仁醫學期刊》 5卷1期 (2007/03) Pp. 43-52

摘要

溶血性尿毒症是造成急性腎衰竭一個重要的原因，而且可能會導致腎臟功能永久的傷害。我們報導一位45歲的婦女，在短暫服用不知名的草藥後，臨床上產生了典型的溶血性尿毒症的情況，在腎臟切片上出現栓塞性微血管病變，吻合此疾病的診斷。病人總共接受了8次的血漿置換術，其臨床表現、以及血液檢查數據才逐漸穩定。但是很不幸的，病人的腎臟功能仍然沒有恢復。至今，仍需仰賴血液透析的治療。有關溶血性尿毒症的臨床表現、發病原因、及病理變化在此也一併討論。

關鍵字

溶血性尿毒症 ； 栓塞性微血管病變 ； 腎衰竭

並列摘要

Hemolytic uremic syndrome (HUS) is an important cause of acute renal failure, and may be irreversible. We describe a 45-year-old woman who developed non-enteropathic HUS soon after taking herbal medicine of unknown composition for a few days. A renal biopsy showed glomerular sclerosis and collapse secondary to the glomerular and vascular lesions of thrombotic microangiopathy. Her clinical condition was stabilized after 8 exchanges of plasmapheresis. However, renal failure persisted, and the patient still depends on long-term dialysis. The clinical manifestations, etiologies, and pathologic findings of HUS are discussed.

並列關鍵字

hemolytic-uremic syndrome ； thrombotic microangiopathy ； renal failure ； herbs