The upsurge of nosocomial infections due to multidrug-resistant Acinetobacter baumannii (MDRAB) has been noticed, particular in critically ill patients and those with significant underlying diseases. The emergence of pandrug-resistant Acinetobacter baumannii (PDRAB) strains that are resistant to all commercially available antibiotics has also been observed in recent years. In Taiwan, the first appearance of PDRAB was in 1998 at the National Taiwan University Hospital (NTUH) and the widespread presence of this organism has been evident ever since. Six years after the first appearance of PDRAB, we report on the first pandrug-resistant A. baumannii nosocomial bacteremia case in Taipei City Hospital, Yangming Branch.