Klebsiella Pneumoniae Osteomyelitis and Arthritis in Adults

克雷白桿菌肺炎對成人骨骼或關節的感染

林建中(Chien-Chung Lin) ； 劉陳愛勤(Ai-Chin Liu Chen) ； 曾永輝(Yang-Hwei Tsuang)

《北市醫學雜誌》 3卷8期 (2006/08) Pp. 757-763

https://doi.org/10.6200/TCMJ.2006.3.8.01

摘要

Klebsiella是社區及院內感染中很有名的細菌，也是世界上臨床醫師最常遇見的細菌感染之一。Klebsiella Pneumoniae因為具有廣效的beta-Lactamase這種酵素，而能夠對許多種抗生素產生抗藥性。又其具有第1及3型的纖毛，使Klebsiella Pneumoniae能夠輕易附著在生物及非生物的表面上，因此能夠轉移到全身的器官。雖然Klebsiella Pneumoniae有可能可以感染全身的每一個地方，但是骨骼及關節的感染在文獻上卻是很少被提到。隨著抗生素的濫用，可以預期末來Klebsiella Pneumoniae的感染會比過去還多而且更嚴重。此篇文章要綜論Klebsiella Pneumoniae在骨骼及關節的感染，以期提醒臨床醫師要重視此菌在骨骼及關節的感染。

關鍵字

Klebsiella Pneumoniae ； 骨骼或關節感染 ； 抗藥性

並列摘要

Klebsiella is a well-known pathogen associated with the community as well as hospital acquired bacterial infections and is among the most common gram-negative bacteria encountered by clinicians worldwide. Extended-spectrum beta-lactamase enables Klebsiella Pneumoniae to possess multi-resistance to antibiotics. Type 1 and 3 pili give KP the ability to adhere to biotic (living) and abiotic (non-living) surfaces and to metastasize around the entire body. Although Klebsiella pneumoniae infections can occur at nearly any body site, bone or joint infections are rarely reported and noted in the literature. Klebsiella infections are encountered far more often now than in the past. In clinical practices orthopedic surgeons will encounter this bacterium more frequently in the future. The article will review bone and joint infections caused by the Klebsiella Pneumoniae.

並列關鍵字

Klebsiella Pneumoniae ； bone or joint infections ； antibiotic resistance