糞便潛血的免疫學試驗

自1982年以來，癌症就已躍居成為國人的第一大死因。大腸直腸癌目前更是國人癌症死因的第三位，因此非常值得我們來研究與探討。根據許多研究顯示，癌症若能早期發現，即愈有治癒的機會，其中大腸癌更是如此，因此大腸癌的篩檢工作更顯重要。但是由於大腸癌的早期症狀常是隱晦不明且特異性不高，極易被病患及醫師所忽視，以致延誤了早期診斷及治療的時機。大腸癌篩檢除了有侵入性的的肛門指診與大腸鏡之外，最為民眾接受的篩檢方式就是糞便潛血試驗。但傳統的糞便潛血化學法敏感度及專一性都不佳，極易受食物或其他因素干擾而不利篩檢。至於免疫法雖然較貴，但是不會受到飲食的干擾，且敏感度及專一性明顯優於傳統化學法，對大量篩檢計畫較為有利，非常值得大規模的推行。

關鍵字

大腸直腸癌篩檢；糞便潛血試驗；化學法；免疫法

並列摘要

Cancer has been the No. 1 cause of death since 1982 in Taiwan. And the No.3 cause of death due to cancer is the colorectal cancer now. This disease is curable only when diagnosed early enough before gross metastases occur. Unfortunately, symptoms of colorectal cancer are nonspecific in diagnosis. For earlier and efficient diagnosis of colorectal cancer, we need a rapid and high sensitivity screening test. The most popular screening test for colorectal cancer is the fecal occult blood tests (FOBT) now. The immunological FOBT is more expensive than the traditional test (chemical test), but the immunological FOBT is more specific and sensitive than another. On the other hand, the immunological test has the less interferences. We think the new immunological FOBT is the ideal large-scale screening test for colorectal cancer.

並列關鍵字

the screening test of colorectal cancer ； fecal occult blood test FOBT ； chemical test ； immunological test

國際替代計量

糞便潛血的免疫學試驗

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