長期低劑量輻射照射與乳房超音波結果異常之分析

The Association between Long-term Low-dose Irradiation and Abnormal Breast Ultrasound Findings

盛業瑄(Yueh-Hsuan Sheng) ； 吳岱穎(Tai-Yin Wu) ； 陳哲民(Jer-Min Chen) ； 林光洋(Kuang-Yang Lin) ； 陳建志(Chien-Chih Chen) ； 郭冠良(Kung-Liang Kuo)

《北市醫學雜誌》 7卷1期 (2010/03) Pp. 34-40

https://doi.org/10.6200/TCMJ.2010.7.1.04

摘要

Objectives: The aim of this study was to compare whether there are differences in breast ultrasound findings among various groups of females from different clinical sources. These were women of various ages who were either attending a family medicine outpatient department, undergoing a self-paid health examination or attending a chronic γ-irradiation health examination. Methods: This cross-sectional study enrolled 200 subjects who had received a breast ultrasound examination at a health examination center in Taipei City from October 2005 to February 2009. The age range was from 22 year-old to 78 year-old. Subjects were classified according to where they were attending at the center; these were a self-paid health examination (H group), a family medicine outpatient department (O group) and a chronic γ-irradiation health examination (R group). The results from breast ultrasound examinations were classified either as negative (BIRADS category 1/2) or positive (BIRADS category 0/3/4/5). We used the chi-square test to analyze whether chronic low dose irradiation was correlated with breast ultrasound abnormalities. We fur ther analyzed the results according to age group (before and after menopause) in order to discover whether female hormone levels had an effect on the breast ultrasound findings. Results: The breast ultrasound findings showed a significant difference between the three groups (H/O/R) (x^2=6.02; p＜0.05). However, there was no significant difference between the pre-menopausal and post-menopausal groups (x^2=0.39; p＞0.05). Conclusion: Our study indicates that females who undergo chronic low dose γ-irradiation do not show an increase in abnormal breast ultrasound findings. However, a longer follow up time is needed to explore any long-term effects. Furthermore, women younger than 50 years old do not seem to have a higher frequency of breast ultrasound abnormality than older women.

關鍵字

輻射屋體檢 ； 低劑量輻射 ； 乳房超音波 ； 乳房X光攝影

並列摘要

Objectives: The aim of this study was to compare whether there are differences in breast ultrasound findings among various groups of females from different clinical sources. These were women of various ages who were either attending a family medicine outpatient department, undergoing a self-paid health examination or attending a chronic γ-irradiation health examination. Methods: This cross-sectional study enrolled 200 subjects who had received a breast ultrasound examination at a health examination center in Taipei City from October 2005 to February 2009. The age range was from 22 year-old to 78 year-old. Subjects were classified according to where they were attending at the center; these were a self-paid health examination (H group), a family medicine outpatient department (O group) and a chronic γ-irradiation health examination (R group). The results from breast ultrasound examinations were classified either as negative (BIRADS category 1/2) or positive (BIRADS category 0/3/4/5). We used the chi-square test to analyze whether chronic low dose irradiation was correlated with breast ultrasound abnormalities. We fur ther analyzed the results according to age group (before and after menopause) in order to discover whether female hormone levels had an effect on the breast ultrasound findings. Results: The breast ultrasound findings showed a significant difference between the three groups (H/O/R) (x^2=6.02; p＜0.05). However, there was no significant difference between the pre-menopausal and post-menopausal groups (x^2=0.39; p＞0.05). Conclusion: Our study indicates that females who undergo chronic low dose γ-irradiation do not show an increase in abnormal breast ultrasound findings. However, a longer follow up time is needed to explore any long-term effects. Furthermore, women younger than 50 years old do not seem to have a higher frequency of breast ultrasound abnormality than older women.

並列關鍵字

low dose irradiation ； breast ultrasound ； mammography