This report describes the nursing experience of caring a 49-year-old man with acute myocardial infarction receiving primary cardiac catheterization in emergency room. Data was collected using the Gordon's eleven health function assessments, observations, interviews, and health assessments. Health problems were identified: decreased cardiac output, acute pain, and anxiety. We monitored the tissue perfusion signs, ECG changes and drug efficacy carefully to keep the patient in a more stable hemodynamic status and blood oxygen saturation of 95% or more. In addition, we taught the patient relaxation skills and helped adjusting his lying position which decreased his pain score from 8 to 3. We established a companionship with the patient; we clarified questions in coordination with the care team and shared successful cases with the patient; we encouraged the patient to express his anxiety on the disease and face the disease positively. After this, he agreed to receive the cardiac catheterization.