Combination Therapy of Traditional Chinese and Western Medicine for Liver Cirrhosis and Hepatocellular Carcinoma: A Case Report

中西醫合併治療肝硬化與肝癌－病例報告

呂秉勳(Ping-Hsun Lu) ； 蕭仲凱(Jong-Kai Hsiao) ； 陳建霖(Chien-Lin Chen) ； 許景盛(Ching-Sheng Hsu)

《北市醫學雜誌》 17卷4期 (2020/12) Pp. 482-489

https://doi.org/10.6200/TCMJ.202012_17(4).0011

摘要

Patients with alcoholic liver cirrhosis (ALC) often have a worse prognosis and various complications, including ascites, variceal bleeding, encephalopathy, and hepatocellular carcinoma (HCC). Although combining traditional Chinese medicine (TCM) and Western medicine (WM) has been shown to facilitate the short-term survival of the patients with liver cirrhosis or HCC, the long-term effects of such combination in patients with ALC remain unknown. In this paper, we describe a 73-year-old man with an active alcohol drinking problem and had experienced several episodes of gastrointestinal bleeding, ascites, and encephalopathy over the last 15 years. A liver tumor was identified in his first visit and later proven to be HCC. The patient refused a surgical intervention and any other WM treatment. Instead, he received combined TCM and WM treatments. Although his liver function gradually deteriorated, no significant tumor progression was noted during the follow-up period.

關鍵字

alcoholic liver cirrhosis ； hepatocellular carcinoma ； traditional Chinese medicine ； follow-up studies ； prognosis

並列摘要

酒精性肝硬化患者的預後通常較差，並有多種併發症，包括腹水，食道靜脈曲張破裂出血，肝腦病變和肝細胞癌。儘管已證明將中藥和西藥結合使用可促進肝硬化或肝癌患者的短期生存，但這種結合對ALC患者的長期療效仍未知。在本文中，我們描述了一個73歲長期酗酒的男子，他持續飲酒並在15年內經歷了幾次胃腸道出血，腹水和肝腦病變發作。初診時發現了肝腫瘤，但患者在腫瘤被證實為肝癌後拒絕接受手術和各種可能的西醫肝癌治療方式，並決定採取中藥和西藥的聯合治療。儘管他的肝功能逐漸惡化，但在追蹤期間未觀察到明顯的腫瘤進展與惡化。

並列關鍵字

酒精性肝硬化 ； 肝細胞癌 ； 中藥追蹤研究 ； 預後