This article describes a patient with bladder cancer suffering from physical and mental impairment. Data of observation physical, psychological, social, mental assessment and interview were collected from May 23th to June 11th 2011. The identified problems were hopelessness, malnutrition, change of elimination pattern due to diarrhea and mental distress due to distrust of religion. During the period of care, the author used empathy and communication skills to gain the patient’s trust. In addition, the author helped the patient to face the impact of cancer recurrence, increased his ability of self-health maintenance and felt more comfortable. The author shares this nursing experience as a reference for others who might care for the same patient.