頸動脈非顯影劑磁振血管攝影之可行性評估

The Clinical Feasibility of Non-contrast MR Carotid Angiography

張緯榮(Wei-Jung Chang) ； 林新傑(Hsin-Chieh Lin) ； 邱思穎(See-Ying Chiou) ； 黃偉倫(Wei-Lun Huang) ； 李基訓(Chi-Hsin Lee) ； 李正輝(Cheng-Hui Lee) ； 陳名聖(Ming-Sheng Chern) ； 陳良光(Liang-Kuang Chen) ； 蘇振隆(Jenn-Lung Su)

《台灣應用輻射與同位素雜誌》 6卷2期 (2010/06) Pp. 875-880

https://doi.org/10.29832/TJARI.201006.0004

摘要

在頸動脈的非顯影劑磁振血管攝影(non-contrast enhance MRA)中，常用的掃描波序爲TOF(time of flight)及PC(phase contrast)，但其仍受到複雜血流影響或掃描時間過長的限制，在頸動脈分叉處更容易出現因訊號喪失所產生的假性狹窄，雖然顯影劑磁振血管攝影(contrast enhance MRA)常成爲臨床檢查的替代方式，但對於腎功能異常或顯影劑過敏體質者，仍造成潛在的醫療危險，因此希望以Time-SLIP (Time-Spatial Labeling Inversion Pulse)的新技術搭配3D True-SSFP (True-steady-state free-precession)波序，在不需施打顯影劑下，能夠呈現頸動脈的血管影像，藉由進行Time-SLIP的參數最佳化，找出適合的TI(inversion time)值，並與傳統TOF影像進行比較，評估其影像品質是否能成爲頸動脈臨床檢查的另一項選擇。

關鍵字

頸動脈磁振血管攝影 ； 非顯影劑磁振血管攝影 ； Time-SLIP ； 3D True-SSFP

並列摘要

For non-contrast enhance MR angiography (MRA) of the carotid arteries, the most commonly used pulse sequences are time of flight (TOF) and phase contrast (PC). However, there is still limitation due to complex hemodynamics of the carotid arteries, and prolonged scanning time. At the carotid bifurcation, signal loss frequently results in an imaging feature of ”pseudostenosis”. In such condition, contrast enhanced MRA is an alternative way in clinical practice. However, for those with renal function impairment or allergy to contrast medium, contrast administration is associated with potential risk. Therefore, in our institution, a novel technique called Time-Spatial Labeling Inversion Pulse (Time-SLIP) combined with 3 dimensional true-state free-precession (3D True-SSFP) was applied to achieve images for vasculature detail of the carotid artery without injection of contrast medium. In our study, the optimal parameters for Time-SLIP are tested to find out the best inversion time (TI) value. The imaging quality of Time-SLIP was compared with that of conventional TOF, to evaluate if it can provide another imaging of choice in the clinical application of carotid artery examination.

並列關鍵字

carotid MR angiography ； non-contrast enhance MR angiography ； Time-SLIP ； 3D True-SSFP