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直線加速器在不同治療距離下物理半影區變化情形的探討

The Penumbra Study at Different Source to Skin Distance by Using Mathematical Method in High Energy Radiation Therapy

摘要


使用高能光子射束治療惡性腫瘤的病患時•常會遇見某些重要器官位於射束邊緣區•爲了能精確評估射束邊緣區的劑量分佈並避免射束半影區(penumbra region)照射到重要器官或組織,如上頷竇(maxillary sinus)、鼻腔(nasal cavity)或腮腺(parotid)等部位之治療時,必須避免射束半影區照射到眼睛,才不致超過其耐受劑量(tolerance dose),而產生併發症。因此我們必須要有射束半影區的資料,也就是每部治療機特有的半影寬度表,以供臨床上的劑量評估和治療計畫上之應用。我們使用變色軟片中來測量各種照野在不同治療距離下的射束剖面圖(beam profile),並選擇射束中心軸劑量的20%-80%爲半影區而分別找出多葉式準直儀在不同停留位置下的半影區之大小;另外還根據在2008年於Phys. Med. Biol.所發表之數學試算法比較了變色軟片(Gaf chromic film)在聚苯乙烯(polystyrene)固態假體中之測量結果。我們得到:6 MV光子射束與10 MV光子射束的半影在SSD最小距離時,其20%-80%爲半影區的差值最小;隨著SSD變大距離時;其20%-80%爲半影區的差值也會跟著變大;而當照野愈大與深度愈深時,半影區的範圍也愈大;,對於10 MV光子射束而言•其差別大約0.27 mm以內,對於6 MV光子射束而言•其差別大約0.25 mm以內;而射束中心軸處的50%位置點會隨著光子的能量越大及照野的開大而往多葉式準直儀的方向移動。

並列摘要


The characteristic of penumbra in high energy photon beam radiation therapy is very important to avoid either lesion being under dose or critical organs being overdose. The purpose of this study is to understand the penumbra width at different Source Skin Distance and different multi leaf collimator position on two photon energy in clinical radiotherapy. Method and materials We use Elekta 10 MV, 6 MV linear accelerator at four different SSD (Source Skin Distance), 90 cm, 100 cm, 110 cm, 120 cm and different multi leaf collimator position from -12 to 20 cm to do the penumbra measurement. Mathematical method was also used to evaluate the predicted penumbra for comparison of Gaf Chromic film results. Results: The conclusion of this penumbra study also investigate the importance of treatment planning system of MLC round leaf end position adjustment when split field are used for calculating patients treatment monitor units. How these penumbra positions affected the dose delivery and after correction of the offset parameter to have a good fit between calculated and measurement dose of is the aim of this study.

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