乳癌混合型強度調控放射治療技術之探討

Comparison of Breast Cancer in Different Intensity-Modulated RadiationTherapy Technology

鍾春香(Chun-Hsiang Chung) ； 姚學華(Hsueh-Hua Yao) ； 林招膨(Jao-Perng Lin) ； 李桂樑(Kuei-Liang Li)

《台灣應用輻射與同位素雜誌》 9卷1期 (2013/03) Pp. 521-526

摘要

There will be side effects of breast cancer radiation therapy due to different individuals of the breast tissue and body surface contour. Therefore, the purpose of the development of different treatment techniques was improve tumor control rate and reduce the adverse reactions caused by the surrounding normal tissue due to radiation therapy. In this study, we wanted to find out that the optimized treatment technique by comparing Hybrid IMRT technology and IMRT techniques for patient with breast cancer in different regions of the dose distribution. Evaluation the volume of the ipsilateral lung V20, heart the V30 volume, and contralateral breast V5 volume in 20 patients of breast cancer with conservation andIMRT or hybrid IMRT. Target coverage and homogeneity were similar. For hybrid IMRT, 40.8% of the ipsilateral lung received a dose of ≥5 Gy (V5) and 26.73 % a dose of≥10 Gy (V10). V5 and V10 were found to be 64.78% and 34.93% for IMRT, respectively. For hybrid IMRT, 30.46% of the heart received a dose of ≥5 Gy (V5) and 13.79 % a dose of≥10 Gy (V10). V5 and V10 were found to be 73.18% and 28.75% for IMRT, respectively. The contralateral had higher low-dose effect in IMRT. Target coverage and homogeneity were similar. For hybrid IMRT, 40.8% of the ipsilateral lung received a dose of ≥5 Gy (V5) and 26.73 % a dose of≥10 Gy (V10). V5 and V10 were found to be 64.78% and 34.93% for IMRT, respectively. For hybrid IMRT, 30.46% of the heart received a dose of ≥5 Gy (V5) and 13.79 % a dose of≥10 Gy (V10). V5 and V10 were found to be 73.18% and 28.75% for IMRT, respectively. The contralateral had higher low-dose effect in IMRT.

關鍵字

乳癌 ； 強度調控放射治療 ； 劑量體積 ； 治療規劃

並列摘要

There will be side effects of breast cancer radiation therapy due to different individuals of the breast tissue and body surface contour. Therefore, the purpose of the development of different treatment techniques was improve tumor control rate and reduce the adverse reactions caused by the surrounding normal tissue due to radiation therapy. In this study, we wanted to find out that the optimized treatment technique by comparing Hybrid IMRT technology and IMRT techniques for patient with breast cancer in different regions of the dose distribution. Evaluation the volume of the ipsilateral lung V20, heart the V30 volume, and contralateral breast V5 volume in 20 patients of breast cancer with conservation andIMRT or hybrid IMRT. Target coverage and homogeneity were similar. For hybrid IMRT, 40.8% of the ipsilateral lung received a dose of ≥5 Gy (V5) and 26.73 % a dose of≥10 Gy (V10). V5 and V10 were found to be 64.78% and 34.93% for IMRT, respectively. For hybrid IMRT, 30.46% of the heart received a dose of ≥5 Gy (V5) and 13.79 % a dose of≥10 Gy (V10). V5 and V10 were found to be 73.18% and 28.75% for IMRT, respectively. The contralateral had higher low-dose effect in IMRT. Target coverage and homogeneity were similar. For hybrid IMRT, 40.8% of the ipsilateral lung received a dose of ≥5 Gy (V5) and 26.73 % a dose of≥10 Gy (V10). V5 and V10 were found to be 64.78% and 34.93% for IMRT, respectively. For hybrid IMRT, 30.46% of the heart received a dose of ≥5 Gy (V5) and 13.79 % a dose of≥10 Gy (V10). V5 and V10 were found to be 73.18% and 28.75% for IMRT, respectively. The contralateral had higher low-dose effect in IMRT.

並列關鍵字

Breast Cancer ； Intensity-Modulated Radiation Therapy ； Dose-Volume Histograms ； Treatment Planning