光激發光劑量計應用於迴旋加速器中心劑量評估

本研究採用熱發光劑量計(thermoluminescent dosimeter, TLD)及光激發光劑量計(optical stimulatedluminescence dosimeter, OSLD)，評估醫用迴旋加速器室內、外光子輻射劑量以及工作人員體外輻射曝露，包含工作人員在放射性藥物氟-18去氧葡萄糖(18F fluorodeoxyglucose, 18F-FDG)調劑、運送放射性藥物時、手指部與全身所接受體外劑量。研究方法將 TLD與OSLD佈點於工作人員重要器官的身體表面上，以評估工作人員的體外劑量，將劑量計做3度空間棋盤式佈點於迴旋加速器室上，評估工作環境中的光子輻射劑量分佈。實驗結果顯示，工作人員每週調劑18F-FDG的生產活度1400 mCi所花的時間為40分鐘來推算，該工作人員一年所接受之等價劑量在左眼及右眼分別為14.3 mSv、15.2 mSv，左手及右手分別為232.5 mSv、298.4 mSv；推估一年的有效劑量為8.4 mSv。評估迴旋加速器使用電流強度35 μA所造成的空間光子劑量分佈，加速器主體前端的門縫處劑量為13~22 μGy，而在加速器兩側及後方的劑量皆在6~11 μGy劑量區間範圍內。

關鍵字

迴旋加速器；熱發光劑量計；光激發光劑量計；劑量評估

並列摘要

This study evaluates radiation dose exposure towards laboratory technicians as a function of the cyclotron measurement device used when drawing out ^(18)F fluorodeoxyglucose (^(18)F-FDG) that occurs during processing and transporting if radiation pharmaceuticals. The dose of radiation exposure having accumulated in the technologists is evaluated. To determine the exposure rate, the study measured containing thermoluminescent dosimeter (TLD-700) and optically stimulated luminescence dosimeter (OSLD). TLD-700 and OSLD were attached at various parts of the body not only to determine the dose of radiation exposure found in a technologist, but also to evaluate the radiation risk exposure to sensitive organs that could be received when drawing out of ^(18)F-FDG studied. The gamma dose distribution was acquired by the 3-plane placements of the TLD-700 and OSLD in the space of cyclotron room and transporting the radiation pharmaceuticals (including automobiles and PIG) and the extrapolation code. Experimental results indicated that while drawing out ^(18)F-FDG (1500 mCi 40 min weekly) for a year (50 weeks), the hands of a technologist received the highest dose, with an average of the right finger 298.4 mSv y^(-1) and left finger 232.5 mSv y^(-1). Additionally, the average equivalent doses with protection to the right eye and left were 15.2 mSv y^(-1) and 14.3 mSv y^(-1), respectively. The average whole body effective dose with protection was estimated at 8.4 mSv y^(-1). Devices used include operating the cyclotron for 60 minutes and 35 μA for the beam current, in which the gamma radiation distribution in a cyclotron room were estimated. Experimental results indicated that, at the cyclotron body front, the maximum and mean photon absorption rates are13~22 μGy h^(-1) at the shielding surface; at the cyclotron body lateral or posterior shielding surface, those absorption rates are 6~11 μGy h^(-1).

並列關鍵字

Cyclotron ； TLD ； OSLD ； Dose Evaluation

國際替代計量

光激發光劑量計應用於迴旋加速器中心劑量評估

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