- 期刊
利用電腦斷層心臟鈣化分析與斑塊型態評估冠狀動脈狹窄程度
Using Computed Tomography Calcium Analysis and Types of Plaque to Evaluate the Coronary Artery Stenosis
摘要
現今人們生活習慣的改變，導致罹患心臟病的人數逐年增加。心臟冠狀動脈電腦斷層掃描（Coronary Computed Tomography Angiography, CCTA）是針對心臟血管最方便的檢查之一，但有顯影劑過敏的風險。而冠狀動脈鈣化指數分析（Coronary Artery Calcification Score, CACS）是一種非侵入性的檢查，分數越高表示血管鈣化越嚴重，但分數的高低並不能明確的診斷血管是否狹窄。本研究利用鈣化分數搭配斑塊型態評估每段冠狀動脈血管的狹窄程度。本研究為回溯性的研究，收集55位曾做過CCTA和CACS的病人，並將三條冠狀動脈分為九個部份，搭配鈣化斑塊型態，進行統計分析。結果顯示，斑塊型態與狹窄率的p值分別為RCA：0.018、LAD：0.041、LCX：0.044。每段血管斑塊型態與顯著狹窄之ROC曲線下的面積為：RCA近端：0.734、RCA遠端：0.607、LM：0.620、LAD近端：0.774、LAD中端：0.786、LAD遠端：0.589、LCX近端：0.721、LCX中端：0.621、LCX遠端：0.571。鈣化斑塊型態與狹窄程度有顯著的相關性，能夠提高醫師對於臨床病人診斷的準確度。
並列摘要
Nowadays, individuals' living propensities have changed, and the number of people suffering from heart disease has increased year by year. The Coronary Computed Tomography Angiography (CCTA) is one of the most convenient examinations for the heart and blood vessels, but there is a risk of allergy to the contrast medium. The Coronary Artery Calcification Score (CACS) is a noninvasive examination, and the higher score, the more serious the vascular calcification, but the level of the score can't clearly diagnose whether the blood vessel is stenosis. This study uses the calcification score and plaque types to assess the degree of stenosis of each segment of coronary artery. This examination was review study. It was gathered 55 patients who had gone through CCTA and CACS, and separated the three coronary veins into nine sections, coordinated with calcified plaque for measurable investigation. The results showed that the p-values of plaque types and stenosis rates were RCA: 0.018, LAD: 0.041, and LCX: 0.044, respectively. The zone under the ROC curves of each portion of vascular plaque design and critical stenosis: proximal RCA: 0.734, distal RCA: 0.607, LM: 0.620, proximal LAD: 0.774, middle LAD: 0.786, distal LAD: 0.589, proximal LCX : 0.721, middle LCX : 0.621, distal LCX: 0.571. There was a significant correlation between the types of calcified plaque and the degree of stenosis, which can improve the exactness of doctor diagnosis of clinical patients.
延伸閱讀
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