Many patients are at risk for prolonged bleeding during and following invasive dental procedures, due to congenital and acquired coagulopathy. Dentists often worried about delivering treatment to this special group. The medical history and laboratory tests are critical for identification of patients potentially at risk for prolonged bleeding from dental treatment. The vast majority of patients with suspected coagulopathies are best managed in the community practice setting. Dental treatment of patients with bleeding disorders is best accomplished by dentists who are knowledgeable about the pathology, complications and treatment options associated with these conditions. This article describes normal coagulation mechanism, bleeding abnormalities, preoperative systemic precautions and intraoperative hemostatic management.