摘要
原發性顫抖症是一種不確定病因的慢性長期性病況，但是卻會造成老年人部份之的失能問題，也會造成個人及社會上角色扮演及融入之限制。原發性顫抖症乃以症狀之描述為主，其顫抖的振幅隨著年紀而增加，在六十五歲以上的老年人口中，約占有4%，常被誤為帕金森（氏）病(Parkinson's disease)或帕金森（氏）症(Parkinsonism)，但其與帕金森氏症雖類似，在本質、病程及預後等均明顯不同。原發性顫抖症的致病原因尚不明朗，即使最近幾年對於原發性顫抖症的瞭解有稍為明顯的進展，但是仍然尚有許多不清楚之處。而現今的治療方式不管是藥物或是手術治療，對老年病患來說均有其侷限性，所以我們期許未來可以更加了解其致病機轉，也希望可以發展出更有效的治療方式。
並列摘要
Essential tremor is a benign condition of unknown etiology but associated with substantial disability in older people. Essential tremor that is often misdiagnosed as Parkinson's disease affects about 4% of the population above 65 years of age, and tremor amplitude increases with age. The pathogenesis of essential tremor is not fully understood, and there are still large gaps in our knowledge despite significant progress in our understanding of this condition in recent years. Essential tremor can cause considerable personal and social handicap. Current therapy for essential tremor has significant limitations in the older population. We hope there is a better understanding of the pathophysiology of essential tremor in the future, eventually leading to development of more effective therapy.
延伸閱讀
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