Purpose: The article waspreliminary discussed acne under the Tradition ChineseMedicine diagnosis and treatment based on an overall analysis of the illness and the patient's condition. Method: We were exploredthe relevantfactors of the occurrence and development of acne in the literature of China Medical Journal Network for nearly 22 years(1994-2018), in order to understand the incidence of acne patients and on the medication and common syndromes in recent years,Results: The first four types of common symptoms of acne are respectively: wind-heat syndrome, spleen and stomach dampness syndrome, chongrendisregulation syndrome and intermin-gled phlegm and blood stasis syndrome. Among them, the most common syndrome is wind-heat syndrome whichis appeared 11 times in the literature.Conclusion: These four types of syndromes: wind-heat syndrome, spleen and stomach dampness syndrome, chongrendis regulation syndrome and intermin-gled phlegm and blood stasis syndrome which are better cover the all syndromes of acne. These four types are simple systems and easy to grasp which areconducive to the Traditional Chinese Medical identify patterns and determine treatment in clinical acne.