Hyperlipidemia is blood status when one or several of lipids in serum are higher than normal level. Statins are one class of drug that are commonly used to treat hyperlipidemia. In Chinese medicine, we can reduce the serum lipids by saponins, flavonoids, phenols, alkaloids, polysaccharides, those are found in traditional Chinese medicine. But most of the mechanisms are still unknown. For different types of hyperlipidemia (hypercholesterolemia, hyperlipidemia grade triglycerides, and mixed hyperlipidemia), we may have one or more medicine to use at the same time by checking the laboratory datas. We can also choose medicines by TCM theory. So we may find out most appropriate prescription for individual patient.