Patient safety is essential for medical quality. The goal of patient safety is patients avoid from unnecessary injuries while receiving healthcare service. Patient safety has become a national-wide issue. In order to ensure patient safety culture in healthcare organizations, there are four elements such as reporting culture, just culture, blame-free culture, and learning should be emphasized. Thus, it is possible to input these cultures to administration system and adverse event management, and to cultivate healthcare professionals, belief and attitude with medical error and patient safety concept. To promote patient safety oriented working environment and interdisciplinary collaboration is the way to avoid medication errors caused by system or human factors.