This paper describes the implementing an evidence-based breast care clinical guideline in a medical center in metropolitan Taiwan. Breast cancer is the leading cancer diagnosis for women in Taiwan. The diagnosis can be devastating in one’s life. Early detection of cancer greatly improved the rate of successful treatment. However, the negative emotions and psychological distress during screening, diagnosis and treatment decisions adversely affect thinking and information processing, leading to decreased quality of life. This project established a seamless service model for breast cancer patients that included an integrated examination process, a navigator program and patient-centered care. It begins with the pre-diagnostic period and continues through diagnostic, cancer treatment and five-year follow-up. It is recommended that this seamless cancer patient service model be a benchmark for other cancer navigator programs.