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淺談中老年男性更年期

An Overview of Male Climacteric

摘要


更年期的概念在男性與女性不同,所伴隨的症狀亦有異,女性更年期症狀一般是快速出現並於1~2年達到高峰,然後在短暫的幾年內結束;反觀男性更年期症狀是緩慢進展,甚至會延續幾年。再者,男性在更年期因無第二性徵功能停止之生理問題,故男性更年期較少被注意及探討。男性更年期容易產生自主神經症候群之外,近來研究皆指出男性更年期因性腺功能不足,而導致與代謝症候群、骨質疏鬆、心血管疾病等慢性疾病有顯著關係存在,這可能會造成未來中老年人不可逆的身體殘障,應加以被重視。本文介紹中年男性常見更年期症狀、治療及照護。中年常見疾病所帶來的症狀必須與更年期的自然老化現象清楚分辨,以免延遲就醫。

關鍵字

更年期 中老年人 男性 睪固酮

並列摘要


This article provides an overview on the symptoms, treatment, and care related to male climacteric. The concepts of menopause in males and their associated symptoms are different from that of females. Menopausal symptoms in females usually appear rapidly, reach a peak in 1-2 years and end within a few years. However, symptoms associated with male menopause or male climacteric progress much slower and can last for several years. There is no clear cessation of secondary sexual characteristics in male climacteric compared to females; therefore, male climacteric is often not perceived and seldom discussed. Male climacteric is associated with an increased risk of autonomic nervous syndrome, metabolic syndrome, osteoporosis, cardiovascular disease and other chronic diseases that might be associated with a reduction of gonadal function. These conditions can lead to serious irreversible physical disability in the elderly. It is important to distinguish between symptoms that appear during natural aging process and those caused by male climacteric commonly observed in middle-aged men to avoid unnecessary delay in medical management.

並列關鍵字

andropause middle-aged older adults male testosterone

參考文獻


Bhasin, S., Cunningham, G. R., Hayes, F.J., Matsumoto, A. M., Snyder, P. J., Swerdloff, R. S., & Montori, V. M. (2010). Testosterone therapy in men with androgen deficiency syndromes: An endocrine society clinical practice guideline. Journal of Clinical Endocrinology & Metabolism, 95(6), 2536-2559. doi:10.1210/jc.2009-2354
Chedraui, P., & Pérez-López, F. R. (2013). Nutrition and health during mid-life: Searching for solutions and meeting challenges for the aging population. Climacteric, 16(1), 85-95. doi:10.3109/13697137.2013.802884.
Fernández-Balsells, M. M., Murad, M. H., Lane, M., Lampropulos, J. F., Albuquerque, F., Mullan, R. J., … Montori, V. M. (2010). Clinical review: 1. Adverse effects of testosterone therapy in adult men: A systematic review and meta-analysis. Journal of Clinical Endocrinology and Metabolism, 95(6), 2560-2575. doi:10.1210/jc.2009-2575
Fleishman, S. B., Khan, H., Homel, P., Suhail, M. F., Strebel- Amrhein, R., Mohammad, F., … Suppiah, K. (2010). Testosterone levels and quality of life in diverse male patients with cancers unrelated to androgens. Journal of Clinical Oncology, 28(34), 5054-5060. doi:10.1200/JCO.2010.30.3818
García-Cruz, E., Leibar-Tamayo, A., Romero, J., Piqueras, M., Luque, P., Cardeñosa, O., & Alcaraz, A. (2013). Metabolic syndrome in men with low testosterone levels: Relationship with cardiovascular risk factors and comorbidities and with erectile dysfunction. Journal of Sexual Medicine, 10(10), 2529–2538. doi:10.1111/jsm.12265

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