- 期刊
- OpenAccess
支架置放術之冠狀動脈三維數值分析
Three-dimensional Numerical Simulation in Coronary by Stent Implantation
摘要
在臨床上血管支架置放術已被廣泛使用來治療冠狀動脈疾病，但實行支架置放術後的病患，血管還會再窄化。部分研究指出當血液流過支架區域時，因?支架的幾何結構，致使血流在許多凹槽區域形成渦流，造成血塊在此處停留而形成血栓，使血管再度窄化。本研究探討支架置入血管的情形，並嘗試將血液的流場效應考慮在分析模型中，透過加入氣球膨脹及血管壁的回壓力量計算出支架的變形，然後模擬血流流過含有支架的區域，分析血管壁和支架承受的壓力及流體動力學的效應。這樣一來，就可以透過支架變形後的流場數值模擬，較真實的探討臨床上實施血管支架置放術後血液的流動行?，以瞭解支架外形結構對血液流場的影響。
並列摘要
In this research, we include the vascular flow effect in the study of the coronary artery stent. The deformation of the stent due to the balloon dilatation and the reaction of the artery wall is taken into account to simulate the vascular flow field around it and to observe the pressure distribution against the stent and artery wall. The deformation of the stent resulted from the deformation of the blood vessel may be found out. Through the post-deformation numerical simulation of the flow field passing the stent, we are able to study a more realistic vascular flow behavior after the coronary by stent implantation as well as its influence to the vascular flow field.
延伸閱讀
- 楊朝宏（2011）。應用類神經網路於冠狀動脈支架置放後再狹窄的預測〔碩士論文，臺北醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0007-3006201109573000
- 吳榮州（2004）。某區域醫院冠狀動脈疾病以經皮冠狀動脈氣球擴張術治療與支架治療之成本效果分析〔碩士論文，高雄醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0011-2903200614012324
- 劉中平、吳學明、高憲立（2008）。左主冠狀動脈疾病血管成形術之現況－藥物釋放型支架的影響。內科學誌，19(6)，454-464。https://doi.org/10.6314/JIMT.2008.19(6).02
- Lee, C. H. (2008). 嵌入先驗之三維區域單元競爭演算法：多切面電腦斷層掃描冠狀動脈粥樣硬化影像分割與分析 [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2008.01092
- Shih, T. C., Hsiao, H. D., Chen, P. Y., Tu, C. Y., Tseng, T. I., & Ho, Y. J. (2014). Study of Pre- and Post-Stent Implantation in the Trachea Using Computational Fluid Dynamics. Journal of Medical and Biological Engineering, 34(2), 150-156. https://doi.org/10.5405/jmbe.1240