子宮頸錐狀切片的早產風險

Cervical Conization and the Risk for Preterm Birth

李耀泰(Yiu-Tai Li) ； 陳福民(Fu-Min Chen) ； 郭宗正(Tsung-Cheng Kuo)

《南臺灣醫學雜誌》 8卷2期 (2012/12) Pp. 96-99

https://doi.org/10.6726/MJST.201212_8(2).0007

摘要

所有子宮頸錐狀切片手術，包括電燒圈切除術，都被認為可能導致以後有早產和低體重兒。有些學者報導，子宮頸錐狀切除越深，早產機會越高。可能的原因有二：（1）子宮頸管的粘液栓子含有許多免疫球蛋白和吞噬細胞，對孕婦陰道上行性感染有保護作用，當子宮頸管部分被切除，使粘液栓子減小，因此增加感染和發生早產；（2）部分子宮頸組織被切除，失去支撐因懷孕子宮擴大的壓力。

關鍵字

錐狀切片 ； 早產 ； 子宮頸 ； 上皮內贅瘤

並列摘要

Excisional managements for cervical intraepithelial neoplasia, including loop electrosurgical excision procedure, predispose to preterm birth and low birth weight. A possible adverse effect of conization is unnecessary removal of normal healthy tissue, thereby affecting cervical function. Several investigators found an inverse relationship between cone depth and risk of preterm birth. The cervical mucous plug contains high levels of immunoglobulin and phagocytic cells, and is thought to protect the fetomaternal unit against ascending microbes. The absence of against ascending microbes. The absence of sufficient mucous plugs may increase the risk of infection and preterm delivery. A mechanical weakening of the cervix because of the loss of tissue is another possible explanation.

並列關鍵字

conization ； preterm birth ； cervical intraepithelial neoplasia