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Cerebral Lipiodol Embolism During Transcatheter Arterial Chemoembolization of Hepatocellular Carcinoma: Two Cases Report

經導管動脈化療栓塞肝細胞癌所導致的腦LIPIODOL栓子栓塞:二位病例報告

摘要


Cerebral lipiodol embolism (CLE) is a rare complication of transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). Although the prognosis is generally fair, it still carries risk of poor outcome (12.5 - 20.8 % ). Plausible mechanisms of embolism were proposed, to prevent or predict the complication. But no effective therapy has been shown to stop or reverse the consequence. Here, we report two cases of CLE after TACE, treated with methylprednisolone and heparin, and had a good recovery.

並列摘要


腦LIPIODOL栓子栓塞是以經導管動脈化療栓塞肝細胞癌所導致的罕見併發症。儘管預後一般來說尚可,但仍有12.5-20.8%不良預後的風險。一些可能的致病機轉曾經被提出以期能預防或預測。但目前仍無有效的療法可以阻止或逆轉此併發症。在此,我們報告兩位經導管動脈化療栓塞肝細胞癌所導致的腦 LIPIODOL 栓子栓塞病例,施以甲基培尼皮質醇與肝素治療,而有良好的恢復。

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